Chiang Mai Journal of Science

Print ISSN: 0125-2526 | eISSN : 2465-3845

1,647
Articles
Q3 0.80
Impact Factor
Q3 1.3
CiteScore
7 days
Avg. First Decision

In vitro Anti-aging Activities of Crocodile (Crocodylus siamensis) Blood Extracts

Jiradej Manosroi, Charinya Chankhampan, Worapaka Manosroi and Aranya Manosroi*
* Author for corresponding; e-mail address: a.manosroi@gmail.com
Volume: Vol.44 No.4 (October 2017)
Research Article
DOI:
Received: 28 September 2015, Revised: -, Accepted: 26 January 2016, Published: -

Citation: Manosroi J., Chankhampan C., Manosroi W. and Manosroi A., In vitro Anti-aging Activities of Crocodile (Crocodylus siamensis) Blood Extracts, Chiang Mai Journal of Science, 2017; 44(4): 1334-1346.

Abstract

The objective of this study was to determine anti-aging activities of crocodile (Crocodylus siamensis) blood extracts. The extracts were prepared from the whole blood and the precipitated blood (in which the serum was separated). Each was extracted by six different processes including cold water (WC), hot water (WH), cold ethyl acetate (EC), hot ethyl acetate (EH), cold methanol (MC) and hot methanol (MH). The ethyl acetate and methanol extracts were dried by a hot air oven, while the water extracts and the seperated serum were by lyophilization. The total of 15 extracts was investigated for in vitro anti-aging activities including antioxidant, tyrosinase inhibition and gelatinolytic activity of MMP-2 inhibition on human skin fibroblasts as well as cytotoxicity. The dried blood serum (SR) gave the highest DPPH radical scavenging (SC50 value = 1.83±0.60 mg/ml) and lipid peroxidation inhibition (IPC50 value = 0.91±0.13 mg/ml). The precipitated blood extracted by cold ethyl acetate (POEC) showed the highest metal chelating (MC50 = 0.0085±0.007 mg/ml). The tyrosinase inhibition activity of POEC (IC50 = 0.016±0.003 mg/ml) was higher than kojic acid of 2.25 times. All extracts gave no cytotoxicity at all concentrations except the blood extracted by cold water (CBWC) at 1 mg/ml. The extract which indicated the highest cell viability at 1 mg/ml was the precipitated blood extracted by hot methanol (POMH). The blood extracted by cold ethyl acetate (CBEC) exhibited the highest MMP-2 inhibition activity on human skin fibroblasts with the percentages of pro MMP-2 inhibition at 47.30±10.51%, but lower activity than ascorbic acid of 1.93 times. The result from this study has demonstrated the commercial potential of crocodile blood to be developed as raw materials for an anti-aging product.

Keywords: crocodile blood, Crocodylus siamensis, antioxidant, tyrosinase inhibition, cytotoxicity, MMP-2 inhibition

Related Articles

Phytochemical Profiling and In Vitro Mechanistic Evaluation of Dichloromethane Extract from Phyllanthus emblica Fruit for Cancer Chemoprevention
DOI: 10.12982/CMJS.2025.102.

Sirinya Taya, Chonikarn Singai, Rawiwan Wongpoomchai and Orawan Khantamat

Vol.52 No.6 (November 2025)
Research Article View: 228 Download: 65
Development and Evaluation of Buckwheat-Fortified Mung Bean Extrudates: Effects on Physicochemical, Textural, and Antioxidant Properties
DOI: 10.12982/CMJS.2025.100.

Girish Ningappa Mathad and Jenshinn Lin

Vol.52 No.6 (November 2025)
Research Article View: 282 Download: 65
Exploring The Health Benefits of Ganoderma: Mechanisms of Action and Anti-Diabetic Activities
DOI: 10.12982/CMJS.2025.080.

Samantha C. Karunarathna, Nimesha M. Patabendige, Wenhua Lu, Dongqin Dai and Kalani K. Hapuarachchi

Vol.52 No.6 (November 2025)
Review Article View: 1,101 Download: 422
Regulation of Reactive Oxygen Species Metabolism by Trehalose Application Related to Alleviate Chilling Injury Development in Harvested ‘Kim Ju’ Guava Fruit
DOI: 25.015.

Thanakorn Vichaiya, Sirawich Chotikakham and Sitthisak Intarasit

Vol.52 No.2 (March 2025)
Research Article View: 1,209 Download: 515
Enhancing the Physicochemical Characteristics and Biological Activities of Phenolic-rich ‘Bignay’ (Antidesma bunius (L.) Spreng.) Fruit Beverage by Two-stage Fermentation
DOI: 10.12982/CMJS.2025.011.

Vince Ellison B. Leyeza, Rona Camille M. Lizardo-Agustin, Lloyd Earl L. Flandez and Katherine Ann T. Castillo-Israel

Vol.52 No.2 (March 2025)
Research Article View: 1,348 Download: 406
Effect of Die Temperature and Porang (Amorphophallus mulleri B.) Flour on the Physicochemical Properties, Nutritional Value, Estimated Glycemic Index, and Sensory Evaluation of Brown Rice Snack by a Collet Extruder
DOI: 10.12982/CMJS.2025.003.

Cindytia Selvina Bernas, Sagar Pandappa Kalahal, Domas Galih Patria and Jenshinn Lin

Vol.52 No.1 (January 2025)
Research Article View: 1,758 Download: 378
Exploring the Effect of Incubation pH, Temperature, and In Vitro Digestion on Antioxidant Potential of Mung Bean Protein Hydrolysates
DOI: 10.12982/CMJS.2024.090.

Zohreh Karami and Kiattisak Duangmal

Vol.51 No.6 (November 2024)
Research Article View: 891 Download: 306
Microbiological and Biochemical Characterization, and Sensory Evaluation of Dragon Blood Tea Kombucha
DOI: 10.12982/CMJS.2024.088.

Niphawan Panti, Phatthanapong Therdtatha, Suttida Doungta, Supakan Saenkam, Phisit Seesuriyachan, Pornchai Rachtanapun and Kasirawat Sawangrat

Vol.51 No.6 (November 2024)
Research Article View: 1,462 Download: 1,085
Mitigation of Surface Browning in Fresh-Cut Banana Blossom by Tamarind (Tamarindus indica L.) Pulp Extract: A Role in Regulating ROS Metabolism
DOI: 10.12982/CMJS.2024.035.

Warunee Chomkitichai and Sitthisak Intarasit

Vol.51 No.3 (May 2024)
Research Article View: 1,764 Download: 1,004
Effects of Simulated Digestion on the Bioaccessibility of Phenolic Compounds and Antioxidant Activity of Dehydrated Bignay [Antidesma bunius (L.) Spreng]
DOI: 10.12982/CMJS.2024.032.

Ara Fatima A. Carbonera, Liezl M. Atienza, Maria Amelita C. Estacio, Sheba Mae M. Duque, Rona Camille M. Lizardo-Agustin, and Katherine Ann T. Castillo-Israel

Vol.51 No.2 (March 2024)
Research Article View: 1,370 Download: 480
Effects of Selected Yeasts on the Chemical Profiles and Antioxidant Activity of Fermented Coffee Beans during the Aging Process
DOI: 10.12982/CMJS.2024.016.

Yi-Ting Chang, Pi-Hui Hsu, Mao-Che Chiu and Jui-Yu Chou

Vol.51 No.1 (January 2024)
Research Article View: 1,969 Download: 539
Phytochemical Constituents and Potential of Different Extracts from Eleutherine bulbosa on Skin Infectious Treatment : Anti-fungal, Anti-bacterial, Anti-inflammatory and Cytotoxic Activities
DOI: 10.12982/CMJS.2024.002.

Wannisa Raksamat and Ingorn Kimkong

Vol.51 No.1 (January 2024)
Research Article View: 1,225 Download: 1,545
Effects of Aqueous Extraction Factors on Commercial Protease Inhibitory Activities, Phenolic Acid Profiles and Chemical Properties of Hom Mali-105 Rice (Oryza sativa L.) Bran Extract
DOI: 10.12982/CMJS.2023.054.

Worachai Wongwatcharayothin, Supawan Thawornchinsombut and Akkasit Jongjareonrak

Vol.50 No.5 (September 2023)
Research Article View: 1,495 Download: 942
Evaluation of Alcoholic Extracts of Mucuna pruriens (L.) DC. Var. utilis for Antibacterial, Antioxidant and Cytotoxic Activities toward Human Cancer Cell Lines
DOI: 10.12982/CMJS.2023.045.

Kanokwan Jitpimai, Lukana Ngiwsara, Weeranuch Lang, Thanawan Panichpat, Ratchanee Mingma, Jisnuson Svasti and Jintanart Wongchawalit

Vol.50 No.5 (September 2023)
Research Article View: 2,605 Download: 1,170
Efficacy of Dried Indian Gooseberry Kombucha on a Pre–industrial Scale: Chemical Composition, Antioxidant and Antibacterial Activity
DOI: 10.12982/CMJS.2023.034.

Tharinee Klawpiyapamornkun, Thida Kaewkod, Toungporn Uttarotai, Sunanta Wangkarn, Panee Sirisa-ard, Suwalee Kiatkarun, Yingmanee Tragoolpua and Sakunnee Bovonsombut

Vol.50 No.3 (May 2023)
Research Article View: 1,311 Download: 801
Response to Magnetic Field-Induced Stress on the Demographics and anti-ROS Activity of Aphid Macrosiphum rosae L. (Hemiptera:Aphididae)
DOI: 10.12982/CMJS.2023.001.

Juan He, Jiarui Liu, Meiqi Cheng, Jingyu Sun, Wei Chen and Weidong Pan

Vol.50 No.1 (January 2023)
Research Article View: 1,751 Download: 971
Synthesis and Biological Evaluation of Sulfamoyl Carboxamide Derivatives from Sulfur-containing α-Amino acids
DOI: 10.12982/CMJS.2022.070.

Melford C. Egbujor, Uchechukwu C. Okoro, Attah S. Egu, Vivian I. Okonkwo, Sunday N. Okafor, Chigbundu N. Emeruwa, Pius I. Egwuatu, Odera R. Umeh, Mercy I. Eziafakaego, Ifeanyi S. Amasiatu and David C. Nwobodo

Vol.49 No.4 (July 2022)
Research Article View: 2,369 Download: 387
Determination of Both Total Phenolic Compound and Antioxidant Capacity of Herbal Teas Using Smartphone Digital Imaging
DOI: 10.12982/CMJS.2022.030.

Hau Van Nguyen, Jaroon Jakmunee, Napaporn Youngvises and Pakorn Preechaburana

Vol.49 No.2 (March 2022)
Research Article View: 1,926 Download: 1,405
Genetic Diversity Assessment Through Morphological, Biological, and Molecular Studies Among Thai Holy Basil Landraces and Commercial Cultivars
page: 1500 - 1510

Ponsit Sathapondecha and Sukhuman Whankaew

Vol.48 No.6 (November 2021)
Research Article View: 2,401 Download: 781
Effects of Four Different Washing Agents on Microbial Load, Biochemical Properties, Heavy Metals and Pesticides Residues in Sweet potato leaves (Ipomoea batatas (L.) Lam)
page: 969 - 978

Lim Shu Fang, Kivaandra Dayaa Rao Ramarao, Zuliana Razali and Chandran Somasundram

Vol.48 No.4 (July 2021)
Research Article View: 1,694 Download: 514
Antioxidant and Antiproliferative Properties of a Chinese Water Chestnut Extract and Its Biologically Active Isolated Compounds
page: 1036 - 1044

Jinfeng Yang, Myong Jo Kim, Weiling Chen, Yong Soo Kwon and Ji Hye Yoo

Vol.48 No.4 (July 2021)
Research Article View: 1,216 Download: 129
Investigation of Skin Whitening Property of Soybean Seed Protein; Anti-tyrosinase, Anti-inflammation and Antioxidant
page: 150 - 162

Anupong Joompang, Wisarut Payoungkiattikun, Jirayut Dansuk, Napat Nuramrum, Nisachon Jangpromma, Santi Phosri, Bancha Mahong and Sompong Klaynongsruang*

Vol.48 No.1 (January 2021)
Research Article View: 1,792 Download: 1,198
Berberine Loaded Nanoparticles Induce Apoptosis in Human Fibrosarcoma Cells
page: 123 - 134

Minh Thi Hong Nguyen, Lam Luong Nguyen, Tae-Hee Kim, Won-Kyo Jung and Phuong Thi Mai Nguyen*

Vol.48 No.1 (January 2021)
Research Article View: 1,058 Download: 892
Potent Antioxidant Activities of Half-Sib Families of Eucalyptus camaldulensis Dehnh. Leaf Essential Oils Planted in Thailand and Their Antioxidative Components
page: 112 - 122

Sapit Diloksumpun, Preeya Jeenho, Samran Namkhot, Tharinee Saleepochn, Suwaporn Luangkamin*

Vol.48 No.1 (January 2021)
Research Article View: 1,326 Download: 547
Synthesis, Characterization, Antimicrobial, Antioxidant Activities of Schiff Base and its Transition Metal Complexes
page: 1241 - 1254

Atta Ullah Khan*, Iqbal Hussain and Riaz Ullah

Vol.47 No.6 (November 2020)
Research Article View: 1,244 Download: 594
Antioxidant and Anti-inflammatory Activities of Ethanolic Extract from Hoya kerrii Craib
page: 912 - 925

Patcharawan Sittisart, Benjawan Dunkhunthod and Chokchai Chuea-nongthon

Vol.47 No.5 (September 2020)
Research Article View: 1,537 Download: 736
Multi-response Optimization of Ultrasonic Assisted Enzymatic Extraction of Antioxidant Polysaccharides from Waste Ginkgo biloba Sarcotesta
page: 499 - 512

Gui-Sheng Zhou, Yu-Ping Tang, Yao Li and Jin-Ao Duan

Vol.47 No.3 (May 2020)
Research Article View: 1,235 Download: 2,104
Synthesis of New Zerumbone Derivatives and Their In vitro Anti-cancer Activity
page: 181 - 194

Vu Tien Chinh, Pham Thanh Loan, Vu Xuan Duong, Tran Khac Vu and Luu Van Chinh

Vol.47 No.1 (January 2020)
Research Article View: 1,137 Download: 835
Determination of p-Coumaric Acid by Using a Briggs-Rauscher Oscillating System
page: 1207 - 1218

Waqar Uddin, Saif Ullah, Shafiq ur Rehman, Gang Hu*, Muhammad Yasir Nawabi, Zhaohui Fang*, Saira Sardar and Rooh Ullah

Vol.46 No.6 (November 2019)
Research Article View: 1,128 Download: 465
Antioxidant, Anti-tyrosinase, Anti-aging Potentialsand Safety of Arabica Coffee Cherry Extract
page: 930 - 945

Kanokwan Kiattisin*, Nutjeera Intasai, Nichcha Nitthikan, Thananya Nantarat, Kuan-Han Lee, Wei-Chao Lin, Shang-Chian Lue and Pimporn Leelapornpisid

Vol.46 No.5 (September 2019)
Research Article View: 1,361 Download: 658
Antioxidant and Anti-inflammatory Activities of the Siamese Crocodile (Crocodylus Siamensis) Hemoglobin Hydrolysate Derived from Trypsin and Papain Hydrolysis
page: 915 - 929

Jiraporn Lueangsakulthai, Nicholas Michael, Theeranan Temsiripong, Watcharee Khunkitti, Sompong Klaynongsruang, Nisachon Jangpromma*

Vol.46 No.5 (September 2019)
Research Article View: 1,059 Download: 533
Solvent Extraction and Measurement of Antioxidant Activity and Total Phenolic Content from Capsicum chinense Jacq. Cv Habanero at Different Maturity Stages
page: 661 - 671

Víctor Manuel Moo-Huchin*, María de Lourdes Vargas y Vargas , Jorge Abraham Tamayo-Cortez, Daniel Arcángel López-Sauri, Enrique Sauri-Duch, Alejandro Ortiz-Fernández, César Abraham Can-Cauich, David Betancur-Ancona

Vol.46 No.4 (July 2019)
Research Article View: 1,110 Download: 446
Optimization of Ultrasonic-assisted Extraction Using Taguchi Design and In vivo Activities ofPolysaccharides from Flos populi
page: 510 - 522

Ying Zhang, Jiaxuan Li, Zheng Jia, Jianqing Chen, Chunbo Gao and Zunlai Sheng

Vol.46 No.3 (May 2019)
Research Article View: 1,027 Download: 335
Flow Injection Potentiometric Method Based on Ce(IV)/Ce(III) Redox Reaction for Determination of Total Antioxidant Capacity
page: 295 - 307

Puttaporn Klayprasert, Kritsana Jitmanee, Napaporn Youngvises and Jaroon Jakmunee*

Vol.46 No.2 (March 2019)
Research Article View: 1,032 Download: 341
Anti-inflammatory, Antioxidant Activities and Safety of Coffea arabica Leaf Extract for Alternative Cosmetic Ingredient
page: 284 - 294

Kanokwan Kiattisin, Nichcha Nitthikan, Worrapan Poomanee, Pimporn Leelapornpisid, Helmut Viernstein and Monika Mueller

Vol.46 No.2 (March 2019)
Research Article View: 1,080 Download: 1,020
Pharmaceutical and Cosmeceutical Biological Activities of Hemp (Cannabis sativa L var. sativa) Leaf and Seed Extracts
page: 180 - 195

Aranya Manosroi, Charinya Chankhampan, Bang-on Kietthanakorn, Warintorn Ruksiriwanich, Puxvadee Chaikul, Korawinwich Boonpisuttinant, Mathukorn Sainakham, Worapaka Manosroi, Theeraphong Tangjai and Jiradej Manosroi

Vol.46 No.2 (March 2019)
Research Article View: 1,884 Download: 661
A Comparison of Three Extraction Methods for Phenolic Compounds and Antioxidant Activities from Moringa oleifera Leaves
page: 2779 - 2789

Truong Kim Tai, Jittima Thongklay, Pisipong Meunprasertdee, Papadchaya Kornthattalim and Thammarat Kaaewmanee

Vol.45 NO.7 (November 2018)
Research Article View: 1,273 Download: 948
Phytochemical Investigation and Antioxidant Properties of Different Extracts from Artabotrys harmandii Finet & Gagnep
page: 2338 - 2347

Wararut Bunchareon, Supaporn Pamok, Supap Saenphet and Kanokporn Saenphet

Vol.45 No.6 (September 2018)
Research Article View: 1,105 Download: 458
Comparative GC-MS Analysis, In-vitro Antioxidant and Antimicrobial Activities of the Essential Oils Isolated from the Peel of Omani Lime
page: 1782 - 1795

Amwaj Mohammed Al-Breiki, Huda Mubarak Al-Brashdi, Jamal Nasser Al-Sabahi and Shah Alam Khan

Vol.45 No.4 (July 2018)
Research Article View: 1,368 Download: 365
Antibacterial, Antioxidant Properties and Bioactive Compounds of Thai Cultivated Mushroom Extracts Against Food-borne Bacterial Strains
page: 1713 - 1727

Mathurot Chaiharn, Waya S. Phutdhawong, Doungporn Amornlerdpison and Weerachai Phutdhawong

Vol.45 No.4 (July 2018)
Research Article View: 1,229 Download: 542
Chemometric Profiling of Clinacanthus nutans Leaves Possessing Antioxidant Activities using Ultraviolet-visible Spectrophotometry
page: 1519 - 1530

Hui Wen Chong, Khansa Rezaei, Bee Lynn Chew and Vuanghao Lim*

Vol.45 No.3 (May 2018)
Research Article View: 1,061 Download: 376
Antioxidant and Antimicrobial Properties of Polysaccharides from Rice Brans
page: 1372 - 1382

Siriluck Surin, Phisit Seesuriyachan, Prodpran Thakeow, SangGuan You and Yuthana Phimolsiripol*

Vol.45 No.3 (May 2018)
Research Article View: 1,190 Download: 446
Antioxidant Properties of Crocodylus siamensis Blood Components on H2O2-induced Human Skin Fibroblast Cells
page: 1359 - 1371

Nisachon Jangpromma, Khantheeranut Suttee, Santi Phosri, Tinnakorn Theansungnoen, Jiraporn Lueangsakulthai, Wisarut Payoungkiattikun, Sakda Daduang and Sompong Klaynongsruang*

Vol.45 No.3 (May 2018)
Research Article View: 1,248 Download: 491
Effects of Three Drying Treatments on the Polyphenol Content, Antioxidant and Antimicrobial Properties of Syzygium aromaticum Extract
page: 937 - 948

Suat-HianTan* and Md. Rezaul Karim

Vol.45 No.2 (March 2018)
Research Article View: 1,049 Download: 280
Stability of Anthocyanin Content and Antioxidant Capacity Among Local Thai Purple Rice Genotypes in Different Storage Conditions
page: 927 - 936

Supaporn Yamuangmorn, Bernard Dell, Benjavan Rerkasem and Chanakan Prom-u-thai*

Vol.45 No.2 (March 2018)
Research Article View: 1,565 Download: 609
Phenolic Compounds and Antioxidant Activities of Four Edible Species During Seed Germination
page: 905 - 916

Arthitaya Kawee-ai, Pimpak Phumat, Siriporn Okonogi, Srikarnjana Klayraung and Phisit Seesuriyachan*

Vol.45 No.2 (March 2018)
Research Article View: 1,174 Download: 338
Chemical Characterization of Polyphenols of Egyptian Achillea fragrantissima with In Vitro Antioxidant Study
page: 897 - 904

Tarek F. Eissa, Elena Gonzalez-Burgos, M. Emilia Carretero and M. Pilar Gomez-Serranillos*

Vol.45 No.2 (March 2018)
Research Article View: 1,022 Download: 319
Antibacterial and Antioxidant Activities of 3-O-methyl Ellagic Acid from Stem Bark of Polyalthia longifolia Thw.
page: 858 - 867

Pankaj Kumar Jain, Arjun Patra*+, Swaha Satpathy, Sonika Jain and Saleemulla Khan

Vol.45 No.2 (March 2018)
Research Article View: 1,123 Download: 365
In vitro Anti-aging Activities of Centotheca lappacea (L) desv. (Ya Repair) Extract
page: 846 - 857

Thavatchai Kamoltham, Jiradej Manosroi, Charinya Chankhampan, Worapaka Manosroi and Aranya Manosroi*

Vol.45 No.2 (March 2018)
Research Article View: 1,238 Download: 728
Effect of Drying Process on the Physicochemical Properties and Biological Activities of Enzymatic Protein Hydrolysate from Shiitake Mushroom (Lentinula edodes)
page: 762 - 773

Pasakawee Krittalak*, Banjongsinsiri Panida, Lekhavat Supaporn, Noojuy Nowwapan, Taksima Takunrat and Srimongkoluk Ubolwanna

Vol.45 No.2 (March 2018)
Research Article View: 1,245 Download: 1,017
Absorption and Desorption Behaviour of the Flavonoids from Rubus chingii Hu Fruit on Macroporous Adsorption Resins
page: 331 - 341

Qian Chen, Tian-Tian Zhang and Jian-Guo Jiang

Vol.45 No.1 (January 2018)
Research Article View: 1,012 Download: 280
Evaluation of Antioxidant Capacity and Analysis of Major Phenolic Compounds in Achillea grandifolia by HPLC-DAD with Q-TOF LC/MS Confirmation
page: 287 - 298

Duygu Taşkın, Dilek B. Alkaya and Emre Dölen

Vol.45 No.1 (January 2018)
Research Article View: 1,676 Download: 318
Antioxidant Activity and Starch-digesting Enzyme Inhibition of Selected Thai Herb Extracts
page: 263 - 276

Krittalak Pasakawee, Somdet Srichairatanakool, Thunnop Laokuldilok and Niramon Utama-ang

Vol.45 No.1 (January 2018)
Research Article View: 1,118 Download: 290
Antioxidant, Anti-tyrosinase and Immunomodulatory Activities of the Enzymatic Boiled Venus Clam Hydrolysate
page: 249 - 262

Chanutchamon Sutthiwanjampa and Sang Moo Kim

Vol.45 No.1 (January 2018)
Research Article View: 1,050 Download: 451
Antioxidant, Total Phenolics and Total Flavonoid Content of the Aqueous Extract of Caesalpinia bonducella Seeds
page: 929 - 938

Shruti Shukla* and Archana Mehta

Vol.44 No.3 (July 2017)
Research Article View: 1,146 Download: 474
Total Phenolic and Ascorbic Acid Contents and Antioxidant Activities of Twelve Different Ecotypes of Phyllanthus emblica from Pakistan
page: 904 - 911

Syed Mubashar Sabir*, Rashad Hussain Shah and Asad Hussain Shah

Vol.44 No.3 (July 2017)
Research Article View: 1,041 Download: 516
Innovating Botanical Extraction through Application of Microwaves for the Efficient Extraction of Ursolic Acid from Ocimum sanctum Leaves
page: 869 - 880

Rajendra Mehta, Raj Kumar, Roshni Tandey and Vivekananda Mandal*

Vol.44 No.3 (July 2017)
Research Article View: 1,011 Download: 304
Proteomics Profiling and Inflammatory Factor Gene Expression in LPS-Stimulated RAW 264.7 Cells Treated with Crocodylus siamensis Hemoglobin
page: 800 - 815

Nisachon Jangpromma, Natthiya Poolperm, Khanittra Pornsri, Preeyanan Anwised, Thai Kabbua,

Vol.44 No.3 (July 2017)
Research Article View: 972 Download: 428
Carotenoid Composition and Antioxidant Activity of Extracts From Tropical Fruits
page: 605 - 616

V ctor M. Moo-Huchin [a], Gustavo A. Gonz lez-Aguilar [b], Mariela Moo-Huchin [c], Elizabeth Ortiz-V zquez [d], Luis Cuevas-Glory [d], Enrique Sauri-Duch [d] and David Betancur-Ancona* [e]

Vol.44 No.2 (April 2017)
Research Article View: 1,057 Download: 1,054
Antioxidant and Antimicrobial Properties of a Brown Alga Scytosiphon lomentaria
page: 595 - 604

Xiao Juan Xu, Yu Zhang, Hong Lin, Chao Kang, Xiao Ting Fu*

Vol.44 No.2 (April 2017)
Research Article View: 1,064 Download: 277
Antioxidant Activities and Stability of Seed Kernel Extracts from Mango (Mangifera indica linn.) Cultivated in Northern Thailand
page: 573 - 583

Nichana Nakpanich, Wantida Chaiyana and Pimporn Leelapornpisid*

Vol.44 No.2 (April 2017)
Research Article View: 1,156 Download: 401
Evaluation of Biphenylalanine and Its Derivatives as Potential HIV-1 gp120 Attachment Inhibitors Based on Molecular Docking, CD4 Capture ELISA and Cytotoxicity Analysis Entry Inhibitor of HIV-1 gp120
page: 487 - 493

Teow Chong Teoh* [a], Hussin A. Rothan [b] and Mohammed Rizman Idid [a,c]

Vol.44 No.2 (April 2017)
Research Article View: 917 Download: 302
Chemical Profiles and Antimicrobial Activities of Thai Propolis Collected from Apis mellifera
page: 438 - 448

Sirikarn Sanpa [a,b], Milena Popova [c], Tawee Tunkasiri [d], Sukum Eitssayeam [d], Vassya Bankova [

Vol.44 No.2 (April 2017)
Research Article View: 1,891 Download: 473
Phytochemical Screening, Phenolic and Flavonoid Contents, Antioxidant and Cytotoxic Activities of Graptophyllum pictum (L.) Griff.
page: 193 - 202

Nadechanok Jiangseubchatveera, Saisunee Liawruangrath, Aphiwat Teerawutgulrag, Dammrong Santiarwor

Vol.44 No.1 (JANUARY 2017)
Research Article View: 1,271 Download: 686
Polyphenol Contents, Antioxidant and Anticancer Activity (MCF-7) of Soybean Products in Thailand
page: 176 - 183

Thidarat Somdee *, Udomsak Mahaweerawat, Jindawan Wibulutai, Namphuang Dungkokruad and Suneerat Yung

Vol.44 No.1 (JANUARY 2017)
Research Article View: 1,143 Download: 1,909
Ultrasonic Extraction, Antioxidant and Anti-glycation Activities of Polysaccharides from Gynura divaricata Leaves
page: 144 - 156

Pawinee Deetae*[a, e], Kwanrudee Tseng [a], Chanathinart Pasuphan [a], Atikorn Panya [b], Pawadee Methacanon [c], Waranya Temthawee [a] and Manop Suphantharika [d]

Vol.44 No.1 (JANUARY 2017)
Research Article View: 2,318 Download: 413
Phenolic Profile, Fatty Acid and Essential Oil Composition Analysis and Antioxidant, Antialzheimer and Antibacterial Activities of Verbascum flavidum Extracts
page: 1090 - 1101

Mehmet Boğa*[a], Abdulselam Ertaş [b], Nesrin Haşimi [c], Serpil Demirci [d], Mustafa Abdullah Yılmaz [e], Hamdi Temel [f] and Ufuk Kolak [g]

Vol.43 No.5 (OCTOBER 2016)
Research Article View: 1,094 Download: 378
Protein Biomarker Screening on Effect of Freeze Dried Crocodile Blood and Vitamin C in Iron-deficient Anemic Rats
page: 1077 - 1088

Ekawit Threenet [a], Win Chaeychomsri [b], Sudawan Chaeychomsri [c] and Jindawan Siruntaweneti* [b]

Vol.43 No.5 (OCTOBER 2016)
Research Article View: 1,438 Download: 429
Antioxidant Compounds and Activities in Selected Fresh and Blanched Vegetables from Northeastern Thailand
page: 834 - 844

Thidarat Somdee*[a], Udomsak Mahaweerawat [a], Methin Phadungkit [b] and Suneerat Yangyuen [a]

Vol.43 No.4 (JULY 2016)
Research Article View: 1,027 Download: 291
Synthesis, Characterization and Antioxidant Activity of 2-Halobenzoyl Thiourea bearing α- and β-Alanine
page: 578 - 584

Nurziana Ngah*, Nor Azanita Mohamed, and Deny Susanti Darnis

Vol.43 No.3 (APRIL 2016)
Research Article View: 959 Download: 318
Determination of Antioxidant and Anticancer Activities together with Total Phenol and Flavonoid Contents of Cleidion javanicum Bl. and Bridelia retusa (L.) A. Juss.
page: 535 - 546

Duangsuree Sanseera, Boonsom Liawruangrath *, Stephen G. Pyne and Saisunee Liawruangrath*

Vol.43 No.3 (APRIL 2016)
Research Article View: 1,536 Download: 867
Phytochemical Constituents with Antimicrobial and Antioxidant Activities from Xylia xylocarpa (Roxb.) Taub. Sawdust Extracts
page: 11 - 21

Pattarawadee Sumthong Nakmee* [a], Soontree Khuntong [a] and Nitra Nuengchamnong [b]

Vol.43 No.1 (JANUARY 2016)
Research Article View: 1,104 Download: 424
Optimization of the Preparation of Gelatin Hydrolysates with Antioxidative Activity from Lizardfish (Saurida spp.) Scales Gelatin
page: 68 - 79

Sutee Wangtueai [a, b]*, Susanne Siebenhandl-Ehn [c] and Dietmar Haltrich [c]

Vol.43 No.1 (JANUARY 2016)
Research Article View: 1,214 Download: 559
Antioxidant Capacity and Phenolic Content Evaluation on Peanut Skins from 3 Peanut Types
page: 123 - 137

Pornnapa Chuenchom, Prasan Swatsitang, Thanaset Senawong, Sanun Jogloy

Vol.43 No.1 (JANUARY 2016)
Research Article View: 1,135 Download: 594
Insights Into The Causes and Anti-hyperglycemic Effects Of Punica granatum Rind in Alloxan-induced Diabetic Rats
page: 112 - 122

Sushil Kumar Middha [a,c], Talambedu Usha [b]* and Veena Pande [a]

Vol.43 No.1 (JANUARY 2016)
Research Article View: 957 Download: 406
Ameliorating Reactive Oxygen Species-Induced in vitro Lipid Peroxidation in Liver, Carbohydrate and DNA Damage by Dendrocalamus hamiltonii Different Leaf Extracts
page: 80 - 88

Arvind Kumar Goyal [a,b], Sushil Kumar Middha [c], Talambedu Usha [c] and Arnab Sen*[a]

Vol.43 No.1 (JANUARY 2016)
Research Article View: 1,019 Download: 245
Fatty Acid, Essential Oil and Phenolic Compositions of Alcea pallida and Alcea apterocarpa with Antioxidant, Anticholinesterase and Antimicrobial Activities
page: 89 - 99

Abdulselam Ertas*[a,b], Mehmet Boga [b,c], Isil Gazioglu [d], Yeter Yesil [e] , Nesrin Hasimi [f], Cumali Ozaslan [g], Hasibe Yilmaz[h], Muammer Kaplan[j]

Vol.43 No.1 (JANUARY 2016)
Research Article View: 1,067 Download: 379
Comparative Studies on Chemical Composition, Phenolic Compounds and Antioxidant Activities of Brown and White Perilla (Perilla frutescens) Seeds
page: 896 - 906

Sikeret Kongkeaw, Siriporn Riebroy and Manat Chaijan

Vol.42 No.4 (OCTOBER 2015)
Research Article View: 1,097 Download: 349
HPTLC Analysis, Antioxidant, Anti-Inflammatory and Xanthine Oxidase Inhibitory Activity of Plumbago zeylanica L
page: 886 - 895

Shivraj Hariram Nile, Umesh Bapurao Patil and Se Won Park

Vol.42 No.4 (OCTOBER 2015)
Research Article View: 1,078 Download: 514
Prediction of Antioxidant Capacity of Thai Vegetable Extracts by Infrared Spectroscopy
page: 657 - 668

Trakul Prommajak, Sang Moo Kim, Cheol-Ho Pan, Sang Min Kim, Suthat Surawang, Nithiya

Vol.42 No.3 (JULY 2015)
Research Article View: 1,104 Download: 334
Determination of the Effects of Adding Milk and Sugar on the Antioxidant Capacity of Oolong Tea by Chemical and Cell Culture-Based Antioxidant Assays
page: 699 - 711

Angkana Wipatanawin, Sudarat Phongsawanit, Thadthanan Maneeratprasert, Sittiwat Lertsiri

Vol.42 No.3 (JULY 2015)
Research Article View: 1,198 Download: 377
Fatty Acid Composition, Physical Properties, Acute Oral Toxicity and Antioxidant Activity of Crude Lipids from Adipose Tissue of Some Commercialized Freshwater Catfish
page: 626 - 636

Wiwat Wangcharoen, Kriangsak Mengumphan and Doungporn Amornlerdpison

Vol.42 No.3 (JULY 2015)
Research Article View: 1,017 Download: 265
Phenolics production from a novel substrate palm oil mill effluent by Aspergillus niger IBS-103ZA: Evaluation of fermentation conditions and antioxidant activity
page: 1 - 16

Zulkarnain Mohamed Idris, Parveen Jamal, Md Zahangir Alam, Abdul Haseeb Ansari, A

Vol.42 No.1 (JANUARY 2015)
Research Article View: 1,072 Download: 311
In vitro Antioxidant and Antitumor Activities of an Endophytic Fungus Phomopsis liquidambari QH4 from Artemisia annua
page: 992 - 1006

Yixin Qian [a, b], Jichuan Kang*[a, c], Lu Wang [a], Bangxing Lei [a] and Kevin D. Hyde [d, e]

Vol.41 No.5/1 (OCTOBER 2014)
Research Article View: 1,056 Download: 305
Gastroprotective Effects and Antioxidant Activities of Paederia pilifera Hook.f. Root Extract
page: 1121 - 1131

Kantarat Jirakittirat, Supap Saenphet and Kanokporn Saenphet*

Vol.41 No.5/1 (OCTOBER 2014)
Research Article View: 916 Download: 269
Phenolic acids content and antioxidant capacity of fruit extracts from Thailand
page: 636 - 642

Nattaya Ongphimai [a], Supathra Lilitchan*[a], Kornkanok Aryusuk [b], Akkarach Bumrungpert [a], et a

Vol.40 No.4 (OCTOBER 2013)
Research Article View: 1,075 Download: 366
Physical Characteristics and Biological Activities of Thai Flower Extracts Loaded in Niosomes
page: 603 - 617

Aranya Manosroi*[a,b], Bang-on Kietthanakorn [b], Charinya Chankhampan [b], Narinthorn Khositsuntiwo

Vol.40 No.4 (OCTOBER 2013)
Research Article View: 1,059 Download: 361
Role of Quercetin and L-Arginine in Alleviating Zinc Oxide Nanoparticle Hepatotoxicity in Rats
page: 577 - 592

Nayira A. Abdel Baky [a]*, L.M. Faddah [a] , Nouf M. Al-Rasheed [a], Nawal M. Al-Rasheed [a] , and W

Vol.40 No.4 (OCTOBER 2013)
Research Article View: 1,028 Download: 321
The Potential of Electrospun Poly(L-lactic Acid) Fiber Mats Containing a Crude Garcinia Dulcis Extract for Use as Wound Dressings
page: 517 - 533

Orawan Suwantong *[a], Porntipa Pankongadisak [a], Suwanna Deachathai [a] and Pitt Supaphol [b]

Vol.40 No.3 (JULY 2013)
Research Article View: 1,013 Download: 314
Development of Sequential Injection Analysis Using Peristaltic Pump and Electrochemical Detection for Antioxidant Capacity Test by ABTS Assay
page: 224 - 231

Jakkrapun Kongkedsuk [a], Apisake Hongwitayakorn [a], Wannarekha Bootnapang [b], Nisachon Boonto [b

Vol.40 No.2 (APRIL 2013)
Research Article View: 1,454 Download: 338
Antimicrobial and Antioxidant Activities of Methanol, Dichloromethane and Ethyl Acetate Extracts of Scutellaria lindbergii Rech.f.
page: 49 - 59

Bibi Sedigheh Fazly-Bazzaz *[a], Atefeh Arab [b], Seyed Ahmad Emami [c], Javad Asili [c], Mohamad Ha

Vol.40 No.1 (JANUARY 2013)
Research Article View: 1,030 Download: 333
Antioxidant Potential of Pleurotus porrigens Extract and Application in Sunflower Oil during Accelerated Storage
page: 34 - 48

Hip Seng Yim*[a, b], Fook Yee Chye [b], Mei Lian Liow [a], and Chun Wai Ho [a]

Vol.40 No.1 (JANUARY 2013)
Research Article View: 1,062 Download: 359
Antioxidant and Sensory Properties of Thai Herbal Teas with emphasis on Thunbergia laurifolia Lindl.
page: 599 - 609

Eric W.C. Chan*, Suit Ying Eng, Yuen Ping Tan, Zhiew Cheng Wong, Phui Yan Lye, and Lea Ngar Tan

Vol.39 No.4 (OCTOBER 2012)
Research Article View: 1,236 Download: 353
Nutritional and Physicochemical Qualities of Thua Nao (Thai Traditional Fermented Soybean)
page: 562 - 574

Katekan Dajanta1,2, Ekachai Chukeatirote3,* and Arunee Apichartsrangkoon2

Vol.39 No.4 (OCTOBER 2012)
Research Article View: 1,003 Download: 342
Antioxidant, Antibacterial, Anticancer Activities and Chemical Constituents of the Essential Oil from Mesua ferrea Leaves
page: 455 - 463

Sukanya Keawsa-ard* [a] and Samart Kongtaweelert [b]

Vol.39 No.3 (JULY 2012)
Research Article View: 1,112 Download: 626
In vitro INHIBITION OF LIPID PEROXIDATION AND THE ANTIOXIDANT SYSTEM OF ENDOPHYTIC FUNGI FROM THAI MEDICINAL PLANTS
page: 429 - 444

Teerayut Theantana [a,b], Duangta Kanjanapothi [c], Saisamorn Lumyong* [b]

Vol.39 No.3 (JULY 2012)
Research Article View: 1,046 Download: 294
Biological Activities of Supercritical Carbon Dioxide Fluid (scCO2) Extracts from Medicainal Flowers
page: 84 - 96

Bang-on Kietthanakorn, Warintorn Ruksiriwanich, Worapaka Manosroi, Jiradej Manosroi and Araya Manosr

Vol.39 No.1 (JANUARY 2012)
Research Article View: 930 Download: 629
Antifungal and Cytotoxic Activity ofEverniastrum cirrhatum (Fr.) Hale
page: 76 - 83

Prasith Kekuda T. Ramamoorthy, Raghavendra H. LakshmanaShetty, Swathi Devidas, Venugopal T. Mudduraj

Vol.39 No.1 (JANUARY 2012)
Research Article View: 896 Download: 379
Comparative Analysis of Aqueous Extracts of Amaranth and Coriander in Scavenging Free Radical Activity and Protection of DNA against Oxidative Damage
page: 560 - 571

Asmita Dutta and Mukesh Singh

Vol.38 No.4 (OCTOBER 2011)
Research Article View: 1,024 Download: 404
Antioxidant Capacity of Broccoli Seeds Grown in Thailand
page: 117 - 122

Sarunya Chuanphongpanich* [a], Maitree Suttajit [b], Sukon Phanichphant [c Duang Buddhasukh [c]

Vol.33 No.1 (JANUARY 2006)
Research Article View: 1,030 Download: 367
Extraction of Phenolic Compounds from Fruits of Bitter Melon (Momordica charantia ) with Subcritical Water Extraction and Antioxidant Activities of These Extracts
page: 123 - 130

Parichat Budrat and Artiwan Shotipruk

Vol.35 No.1 (JANUARY 2008)
Research Article View: 1,084 Download: 677
Red Yeast Rice Prepared from Thai Glutinous Rice and the Antioxidant Activities
page: 42 - 49

Em-on Chairote, Griangsak Chairote, and Saisamorn Lumyong

Vol.36 No.1 (JANUARY 2009)
Research Article View: 1,200 Download: 374
L-Asparaginase Production by Bipolaris sp. BR438 Isolated from Brown Rice in Thailand
page: 160 - 164

Kodchakorn Lapmak, Saisamorn Lumyong, Sutheera Thongkuntha, Pairote Wongputtisin, and Uraporn Sardsu

Vol.37 No.1 (JANUARY 2010)
Short Communication View: 1,080 Download: 286
Screening of Antioxidants from Some Thai Vegetables and Herbs
page: 1 - 5

Anchana Chanwitheesuk, Nuansri Rakariyatham*, Aphiwat Teerawutgulrag and Teerapol Wongchanapiboon

Vol.29 No.1 (APRIL 2002)
Opinion View: 1,185 Download: 367
Antioxidant and Anti-inflammatory Activities of Brown Marine Alga, Padina minor Yamada
page: 507 - 516

Yuwadee Peerapornpisal, Doungporn Amornlerdpison, Utan Jamjai, Tawat Taesotikul, Yanee Pongpaibul,

Vol.37 No.3 (SEPTEMBER 2010)
Research Article View: 1,090 Download: 375
In vitro Antioxidant Activity of Vitex negundo L. Leaf Extracts
page: 489 - 497

Raghavendra H. Lakshmanashetty, Vijayananda B. Nagaraj, Madhumathi G. Hiremath and Vadlapudi Kumar

Vol.37 No.3 (SEPTEMBER 2010)
Research Article View: 1,591 Download: 1,186
Anti-Cancer Compound Screening and Isolation: Coscinium fenestratum Tinospora crispa and Tinospora cordifolia
page: 476 - 488

Rudeewan Tungpradit, Supachok Sinchaikul, Suree Phutrakul, Weerah Wongkham and Shui-Tein Chen

Vol.37 No.3 (SEPTEMBER 2010)
Research Article View: 1,026 Download: 1,032
Outline
Figures