In vitro INHIBITION OF LIPID PEROXIDATION AND THE ANTIOXIDANT SYSTEM OF ENDOPHYTIC FUNGI FROM THAI MEDICINAL PLANTS

Teerayut Theantana [a; b]; Duangta Kanjanapothi [c]; Saisamorn Lumyong [b]

In vitro INHIBITION OF LIPID PEROXIDATION AND THE ANTIOXIDANT SYSTEM OF ENDOPHYTIC FUNGI FROM THAI MEDICINAL PLANTS

Teerayut Theantana [a,b], Duangta Kanjanapothi [c], Saisamorn Lumyong* [b]
* Author for corresponding; e-mail address: saisamorn.l@cmu.ac.th
Volume: Vol.39 No.3 (JULY 2012)
Research Article
DOI:
Received: 22 September 2011, Revised: -, Accepted: 21 March 2012, Published: -

Citation: Theantana T., Kanjanapothi D. and Lumyong S., In vitro INHIBITION OF LIPID PEROXIDATION AND THE ANTIOXIDANT SYSTEM OF ENDOPHYTIC FUNGI FROM THAI MEDICINAL PLANTS, Chiang Mai Journal of Science, 2012; 39(3): 429-444.

Abstract

Endophytic fungi from medicinal plants have been recognized to be a valuable source of metabolites and novel bioactive compounds. The present work was carried out to examine the antioxidant capacity of thirty-nine endophytic fungi obtained from five Thai medicinal plants which are commonly used in Thai traditional medicines. Their total phenolic content showed a positive correlation with ABTS⁺ radical scavenging activity (R²=0.4009) and reducing power (R²=0.7247) but was not correlated with DPPH radical scavenging activity. Phenolic compounds are the main antioxidant components of reducing power and other secondary metabolites may play a role as the main free radical scavengers. Among thirty-nine endophytic strains, Eupenicillium shearii CMU 18 showed the highest number of phenolic compounds, ABTS⁺ radical scavenging effect, highest reduction potential, and highest lipid peroxidation inhibition activity (IC₅₀ value of 43.46 mg ml^-1) in the rat liver tissue. According to the cytotoxicity test, E. shearii CMU 18 was not cytotoxic. The findings from the present study provide evidence that endophytic fungi from Thai medicinal plants have a potential as a source of antioxidants.

Keywords: endophytic fungi, antioxidant, lipid peroxidation, Thai medicinal plants

Comparative Analysis of Leaf Micromorphology, Phytochemical Profiles, and Antioxidant Activity in Two Vallaris Species (Apocynaceae)
DOI: 10.12982/CMJS.2026.039.

Siriphan Sukkhaeng, Piyanan Thanomchat, Sunipa Detpitthayanan and Yupadee Paopun*

Vol.53 No.3 (May 2026)
Research Article View: 754 Download: 156

Enhancing the Physicochemical Characteristics and Biological Activities of Phenolic-rich ‘Bignay’ (Antidesma bunius (L.) Spreng.) Fruit Beverage by Two-stage Fermentation
DOI: 10.12982/CMJS.2025.011.

Vince Ellison B. Leyeza, Rona Camille M. Lizardo-Agustin, Lloyd Earl L. Flandez and Katherine Ann T. Castillo-Israel

Vol.52 No.2 (March 2025)
Research Article View: 1,884 Download: 441

Effect of Die Temperature and Porang (Amorphophallus mulleri B.) Flour on the Physicochemical Properties, Nutritional Value, Estimated Glycemic Index, and Sensory Evaluation of Brown Rice Snack by a Collet Extruder
DOI: 10.12982/CMJS.2025.003.

Cindytia Selvina Bernas, Sagar Pandappa Kalahal, Domas Galih Patria and Jenshinn Lin

Vol.52 No.1 (January 2025)
Research Article View: 2,285 Download: 411

Microbiological and Biochemical Characterization, and Sensory Evaluation of Dragon Blood Tea Kombucha
DOI: 10.12982/CMJS.2024.088.

Niphawan Panti, Phatthanapong Therdtatha, Suttida Doungta, Supakan Saenkam, Phisit Seesuriyachan, Pornchai Rachtanapun and Kasirawat Sawangrat

Vol.51 No.6 (November 2024)
Research Article View: 2,038 Download: 1,147

Effects of Selected Yeasts on the Chemical Profiles and Antioxidant Activity of Fermented Coffee Beans during the Aging Process
DOI: 10.12982/CMJS.2024.016.

Yi-Ting Chang, Pi-Hui Hsu, Mao-Che Chiu and Jui-Yu Chou

Vol.51 No.1 (January 2024)
Research Article View: 2,310 Download: 560

Evaluation of Alcoholic Extracts of Mucuna pruriens (L.) DC. Var. utilis for Antibacterial, Antioxidant and Cytotoxic Activities toward Human Cancer Cell Lines
DOI: 10.12982/CMJS.2023.045.

Kanokwan Jitpimai, Lukana Ngiwsara, Weeranuch Lang, Thanawan Panichpat, Ratchanee Mingma, Jisnuson Svasti and Jintanart Wongchawalit

Vol.50 No.5 (September 2023)
Research Article View: 3,246 Download: 1,220

Synthesis and Biological Evaluation of Sulfamoyl Carboxamide Derivatives from Sulfur-containing α-Amino acids
DOI: 10.12982/CMJS.2022.070.

Melford C. Egbujor, Uchechukwu C. Okoro, Attah S. Egu, Vivian I. Okonkwo, Sunday N. Okafor, Chigbundu N. Emeruwa, Pius I. Egwuatu, Odera R. Umeh, Mercy I. Eziafakaego, Ifeanyi S. Amasiatu and David C. Nwobodo

Vol.49 No.4 (July 2022)
Research Article View: 2,703 Download: 449

Determination of Both Total Phenolic Compound and Antioxidant Capacity of Herbal Teas Using Smartphone Digital Imaging
DOI: 10.12982/CMJS.2022.030.

Hau Van Nguyen, Jaroon Jakmunee, Napaporn Youngvises and Pakorn Preechaburana

Vol.49 No.2 (March 2022)
Research Article View: 2,293 Download: 1,665

Genetic Diversity Assessment Through Morphological, Biological, and Molecular Studies Among Thai Holy Basil Landraces and Commercial Cultivars
page: 1500 - 1510

Ponsit Sathapondecha and Sukhuman Whankaew

Vol.48 No.6 (November 2021)
Research Article View: 2,658 Download: 789

Antioxidant and Antiproliferative Properties of a Chinese Water Chestnut Extract and Its Biologically Active Isolated Compounds
page: 1036 - 1044

Jinfeng Yang, Myong Jo Kim, Weiling Chen, Yong Soo Kwon and Ji Hye Yoo

Vol.48 No.4 (July 2021)
Research Article View: 1,374 Download: 137

Investigation of Skin Whitening Property of Soybean Seed Protein; Anti-tyrosinase, Anti-inflammation and Antioxidant
page: 150 - 162

Anupong Joompang, Wisarut Payoungkiattikun, Jirayut Dansuk, Napat Nuramrum, Nisachon Jangpromma, Santi Phosri, Bancha Mahong and Sompong Klaynongsruang*

Vol.48 No.1 (January 2021)
Research Article View: 2,043 Download: 1,210

Antioxidant and Anti-inflammatory Activities of Ethanolic Extract from Hoya kerrii Craib
page: 912 - 925

Patcharawan Sittisart, Benjawan Dunkhunthod and Chokchai Chuea-nongthon

Vol.47 No.5 (September 2020)
Research Article View: 1,847 Download: 754

Antioxidant, Anti-tyrosinase, Anti-aging Potentialsand Safety of Arabica Coffee Cherry Extract
page: 930 - 945

Kanokwan Kiattisin*, Nutjeera Intasai, Nichcha Nitthikan, Thananya Nantarat, Kuan-Han Lee, Wei-Chao Lin, Shang-Chian Lue and Pimporn Leelapornpisid

Vol.46 No.5 (September 2019)
Research Article View: 1,577 Download: 669

Antioxidant and Anti-inflammatory Activities of the Siamese Crocodile (Crocodylus Siamensis) Hemoglobin Hydrolysate Derived from Trypsin and Papain Hydrolysis
page: 915 - 929

Jiraporn Lueangsakulthai, Nicholas Michael, Theeranan Temsiripong, Watcharee Khunkitti, Sompong Klaynongsruang, Nisachon Jangpromma*

Vol.46 No.5 (September 2019)
Research Article View: 1,220 Download: 538

Anti-inflammatory, Antioxidant Activities and Safety of Coffea arabica Leaf Extract for Alternative Cosmetic Ingredient
page: 284 - 294

Kanokwan Kiattisin, Nichcha Nitthikan, Worrapan Poomanee, Pimporn Leelapornpisid, Helmut Viernstein and Monika Mueller

Vol.46 No.2 (March 2019)
Research Article View: 1,254 Download: 1,027

Pharmaceutical and Cosmeceutical Biological Activities of Hemp (Cannabis sativa L var. sativa) Leaf and Seed Extracts
page: 180 - 195

Aranya Manosroi, Charinya Chankhampan, Bang-on Kietthanakorn, Warintorn Ruksiriwanich, Puxvadee Chaikul, Korawinwich Boonpisuttinant, Mathukorn Sainakham, Worapaka Manosroi, Theeraphong Tangjai and Jiradej Manosroi

Vol.46 No.2 (March 2019)
Research Article View: 2,194 Download: 669

Phytochemical Investigation and Antioxidant Properties of Different Extracts from Artabotrys harmandii Finet & Gagnep
page: 2338 - 2347

Wararut Bunchareon, Supaporn Pamok, Supap Saenphet and Kanokporn Saenphet

Vol.45 No.6 (September 2018)
Research Article View: 1,280 Download: 466

Comparative GC-MS Analysis, In-vitro Antioxidant and Antimicrobial Activities of the Essential Oils Isolated from the Peel of Omani Lime
page: 1782 - 1795

Amwaj Mohammed Al-Breiki, Huda Mubarak Al-Brashdi, Jamal Nasser Al-Sabahi and Shah Alam Khan

Vol.45 No.4 (July 2018)
Research Article View: 1,565 Download: 372

Chemometric Profiling of Clinacanthus nutans Leaves Possessing Antioxidant Activities using Ultraviolet-visible Spectrophotometry
page: 1519 - 1530

Hui Wen Chong, Khansa Rezaei, Bee Lynn Chew and Vuanghao Lim*

Vol.45 No.3 (May 2018)
Research Article View: 1,257 Download: 389

Antioxidant and Antimicrobial Properties of Polysaccharides from Rice Brans
page: 1372 - 1382

Siriluck Surin, Phisit Seesuriyachan, Prodpran Thakeow, SangGuan You and Yuthana Phimolsiripol*

Vol.45 No.3 (May 2018)
Research Article View: 1,455 Download: 456

Antioxidant Properties of Crocodylus siamensis Blood Components on H2O2-induced Human Skin Fibroblast Cells
page: 1359 - 1371

Nisachon Jangpromma, Khantheeranut Suttee, Santi Phosri, Tinnakorn Theansungnoen, Jiraporn Lueangsakulthai, Wisarut Payoungkiattikun, Sakda Daduang and Sompong Klaynongsruang*

Vol.45 No.3 (May 2018)
Research Article View: 1,441 Download: 497

Effects of Three Drying Treatments on the Polyphenol Content, Antioxidant and Antimicrobial Properties of Syzygium aromaticum Extract
page: 937 - 948

Suat-HianTan* and Md. Rezaul Karim

Vol.45 No.2 (March 2018)
Research Article View: 1,213 Download: 281

Phenolic Compounds and Antioxidant Activities of Four Edible Species During Seed Germination
page: 905 - 916

Arthitaya Kawee-ai, Pimpak Phumat, Siriporn Okonogi, Srikarnjana Klayraung and Phisit Seesuriyachan*

Vol.45 No.2 (March 2018)
Research Article View: 1,316 Download: 348

In vitro Antioxidant Evaluation of Wood Vinegars from Carbonization of Wood and Bamboo
page: 868 - 880

Yongyuth Theapparat*, Chanita Ponglimanont, Ausa Chandumpai and Nikhom Laemsak

Vol.45 No.2 (March 2018)
Research Article View: 1,094 Download: 374

Antioxidant, Anti-tyrosinase and Immunomodulatory Activities of the Enzymatic Boiled Venus Clam Hydrolysate
page: 249 - 262

Chanutchamon Sutthiwanjampa and Sang Moo Kim

Vol.45 No.1 (January 2018)
Research Article View: 1,206 Download: 455

Diversity of Endophytic Fungi Isolated from Thai Medicinal Plants (Casearia grewiifolia) in Khon Kaen, Thailand, and their Bioactive Compounds
page: 45 - 59

Natanong Yodsing, Somdej Kanokmedhakul, Wiyada Mongkolthanaruk, Tadanori Aimi, Totsaporn Srisapoomi and Sophon Boonlue

Vol.45 No.1 (January 2018)
Research Article View: 1,578 Download: 685

In vitro Anti-aging Activities of Crocodile (Crocodylus siamensis) Blood Extracts
page: 1334 - 1346

Jiradej Manosroi, Charinya Chankhampan, Worapaka Manosroi and Aranya Manosroi*

Vol.44 No.4 (October 2017)
Research Article View: 1,378 Download: 344

Antioxidant, Total Phenolics and Total Flavonoid Content of the Aqueous Extract of Caesalpinia bonducella Seeds
page: 929 - 938

Shruti Shukla* and Archana Mehta

Vol.44 No.3 (July 2017)
Research Article View: 1,294 Download: 491

Innovating Botanical Extraction through Application of Microwaves for the Efficient Extraction of Ursolic Acid from Ocimum sanctum Leaves
page: 869 - 880

Rajendra Mehta, Raj Kumar, Roshni Tandey and Vivekananda Mandal*

Vol.44 No.3 (July 2017)
Research Article View: 1,165 Download: 313

Lipid Peroxidation of Escherichia coli by Triplet Non-thermal Atmospheric Pressure Plasma Jet
page: 678 - 687

A. Hossienzadeh Colagar* [a,b], O. Alavi [a], F. Sohbatzadeh [b, c]

Vol.44 No.2 (April 2017)
Research Article View: 1,162 Download: 256

Chemical Profiles and Antimicrobial Activities of Thai Propolis Collected from Apis mellifera
page: 438 - 448

Sirikarn Sanpa [a,b], Milena Popova [c], Tawee Tunkasiri [d], Sukum Eitssayeam [d], Vassya Bankova [

Vol.44 No.2 (April 2017)
Research Article View: 2,120 Download: 480

Ultrasonic Extraction, Antioxidant and Anti-glycation Activities of Polysaccharides from Gynura divaricata Leaves
page: 144 - 156

Pawinee Deetae*[a, e], Kwanrudee Tseng [a], Chanathinart Pasuphan [a], Atikorn Panya [b], Pawadee Methacanon [c], Waranya Temthawee [a] and Manop Suphantharika [d]

Vol.44 No.1 (JANUARY 2017)
Research Article View: 2,509 Download: 418

Phenolic Profile, Fatty Acid and Essential Oil Composition Analysis and Antioxidant, Antialzheimer and Antibacterial Activities of Verbascum flavidum Extracts
page: 1090 - 1101

Mehmet Boğa*[a], Abdulselam Ertaş [b], Nesrin Haşimi [c], Serpil Demirci [d], Mustafa Abdullah Yılmaz [e], Hamdi Temel [f] and Ufuk Kolak [g]

Vol.43 No.5 (OCTOBER 2016)
Research Article View: 1,227 Download: 384

Antioxidant Compounds and Activities in Selected Fresh and Blanched Vegetables from Northeastern Thailand
page: 834 - 844

Thidarat Somdee*[a], Udomsak Mahaweerawat [a], Methin Phadungkit [b] and Suneerat Yangyuen [a]

Vol.43 No.4 (JULY 2016)
Research Article View: 1,182 Download: 297

Synthesis, Characterization and Antioxidant Activity of 2-Halobenzoyl Thiourea bearing α- and β-Alanine
page: 578 - 584

Nurziana Ngah*, Nor Azanita Mohamed, and Deny Susanti Darnis

Vol.43 No.3 (APRIL 2016)
Research Article View: 1,096 Download: 328

Phytochemical Constituents with Antimicrobial and Antioxidant Activities from Xylia xylocarpa (Roxb.) Taub. Sawdust Extracts
page: 11 - 21

Pattarawadee Sumthong Nakmee* [a], Soontree Khuntong [a] and Nitra Nuengchamnong [b]

Vol.43 No.1 (JANUARY 2016)
Research Article View: 1,279 Download: 430

Ameliorating Reactive Oxygen Species-Induced in vitro Lipid Peroxidation in Liver, Carbohydrate and DNA Damage by Dendrocalamus hamiltonii Different Leaf Extracts
page: 80 - 88

Arvind Kumar Goyal [a,b], Sushil Kumar Middha [c], Talambedu Usha [c] and Arnab Sen*[a]

Vol.43 No.1 (JANUARY 2016)
Research Article View: 1,134 Download: 250

Fatty Acid, Essential Oil and Phenolic Compositions of Alcea pallida and Alcea apterocarpa with Antioxidant, Anticholinesterase and Antimicrobial Activities
page: 89 - 99

Abdulselam Ertas*[a,b], Mehmet Boga [b,c], Isil Gazioglu [d], Yeter Yesil [e] , Nesrin Hasimi [f], Cumali Ozaslan [g], Hasibe Yilmaz[h], Muammer Kaplan[j]

Vol.43 No.1 (JANUARY 2016)
Research Article View: 1,201 Download: 387

Prediction of Antioxidant Capacity of Thai Vegetable Extracts by Infrared Spectroscopy
page: 657 - 668

Trakul Prommajak, Sang Moo Kim, Cheol-Ho Pan, Sang Min Kim, Suthat Surawang, Nithiya

Vol.42 No.3 (JULY 2015)
Research Article View: 1,240 Download: 341

Marine Derived Fungi of Peninsular Malaysia-a Biochemical Perspective
page: 894 - 909

Audra Shaleena Paliany, Yasodha Sivasothy, Khalijah Awang, Mohammed Rizman-Idid and Siti Aisyah Alia

Vol.41 No.4 (SPECIAL ISSUE 1)
Research Article View: 1,657 Download: 250

Diversity of Endophytic Fungi Associated with Cinnamomum bejolghota (Lauraceae) in Northern Thailand
page: 389 - 398

Nakarin Suwannarach [a], Boonsom Bussaban [a], Wipornpan Nuangmek [b], Eric H.C. McKenzie [c], Kevin

Vol.39 No.3 (JULY 2012)
Research Article View: 1,088 Download: 374

Comparative Analysis of Aqueous Extracts of Amaranth and Coriander in Scavenging Free Radical Activity and Protection of DNA against Oxidative Damage
page: 560 - 571

Asmita Dutta and Mukesh Singh

Vol.38 No.4 (OCTOBER 2011)
Research Article View: 1,197 Download: 411

Antioxidant Capacity of Broccoli Seeds Grown in Thailand
page: 117 - 122

Sarunya Chuanphongpanich* [a], Maitree Suttajit [b], Sukon Phanichphant [c Duang Buddhasukh [c]

Vol.33 No.1 (JANUARY 2006)
Research Article View: 1,159 Download: 374

Extraction of Phenolic Compounds from Fruits of Bitter Melon (Momordica charantia ) with Subcritical Water Extraction and Antioxidant Activities of These Extracts
page: 123 - 130

Parichat Budrat and Artiwan Shotipruk

Vol.35 No.1 (JANUARY 2008)
Research Article View: 1,282 Download: 699

Red Yeast Rice Prepared from Thai Glutinous Rice and the Antioxidant Activities
page: 42 - 49

Em-on Chairote, Griangsak Chairote, and Saisamorn Lumyong

Vol.36 No.1 (JANUARY 2009)
Research Article View: 1,374 Download: 400

Screening of Antioxidants from Some Thai Vegetables and Herbs
page: 1 - 5

Anchana Chanwitheesuk, Nuansri Rakariyatham*, Aphiwat Teerawutgulrag and Teerapol Wongchanapiboon

Vol.29 No.1 (APRIL 2002)
Opinion View: 1,355 Download: 375

Chiang Mai Journal of Science

2,446

Q3 1.0

Q2 1.6

7 days

Outline

Figures and Tables