Chiang Mai Journal of Science

Print ISSN: 0125-2526 | eISSN : 2465-3845

1,647
Articles
Q3 0.80
Impact Factor
Q3 1.3
CiteScore
7 days
Avg. First Decision

Phenolic Profile, Fatty Acid and Essential Oil Composition Analysis and Antioxidant, Antialzheimer and Antibacterial Activities of Verbascum flavidum Extracts

Mehmet Boğa*[a], Abdulselam Ertaş [b], Nesrin Haşimi [c], Serpil Demirci [d], Mustafa Abdullah Yılmaz [e], Hamdi Temel [f] and Ufuk Kolak [g]
* Author for corresponding; e-mail address: mehmetboga1980@gmail.com; mehmet.boga@dicle.edu.tr
Volume: Vol.43 No.5 (OCTOBER 2016)
Research Article
DOI:
Received: 12 December 2014, Revised: -, Accepted: 12 April 2015, Published: -

Citation: Boğa M., Ertaş A., Haşimi N., Demirci S., Yılmaz M.A., Temel H., et al., Phenolic Profile, Fatty Acid and Essential Oil Composition Analysis and Antioxidant, Antialzheimer and Antibacterial Activities of Verbascum flavidum Extracts, Chiang Mai Journal of Science, 2016; 43(5): 1090-1101.

Abstract

This paper is the first report about phytochemical analysis with LC-MS/MS and biological activities of Verbascum flavidum (Boiss.) Freyn & Bornm. Rutin (1077.09±77.47 µg analyte/g extract) and chlorogenic acid (1012.42±97.18 µg analyte/g extract) were determined the most abundant phenolics in V. flavidum. The main components of fatty acid were found to be palmitic (30.3%) and oleic acids (17.9%); while the major essential oils were determined as arachidic acid (16.4%) and α-selinene (8.9%) by GC-MS analysis. In DPPH free radical scavenging activity the methanol extract showed higher activity than BHT with 72.62% inhibition at 100 µg/mL concentration. The methanol and water extracts of V. flavidum showed 86.01 % and 87.39 % inhibition in ABTS cation radical scavenging assay at 100 μg/mL concentration, respectively. The methanol extract showed moderate activity against E. coli with 250±0.3 MIC value and with 15 mm inhibition zone diameter at 30 mg/mL concentration.

Keywords: Verbascum flavidum, antioxidant, anticholinesterase, antimicrobial, LC-MS/MS, GC-MS

Related Articles

Phytochemical Profiling and In Vitro Mechanistic Evaluation of Dichloromethane Extract from Phyllanthus emblica Fruit for Cancer Chemoprevention
DOI: 10.12982/CMJS.2025.102.

Sirinya Taya, Chonikarn Singai, Rawiwan Wongpoomchai and Orawan Khantamat

Vol.52 No.6 (November 2025)
Research Article View: 322 Download: 78
Enhancing the Physicochemical Characteristics and Biological Activities of Phenolic-rich ‘Bignay’ (Antidesma bunius (L.) Spreng.) Fruit Beverage by Two-stage Fermentation
DOI: 10.12982/CMJS.2025.011.

Vince Ellison B. Leyeza, Rona Camille M. Lizardo-Agustin, Lloyd Earl L. Flandez and Katherine Ann T. Castillo-Israel

Vol.52 No.2 (March 2025)
Research Article View: 1,465 Download: 417
Effect of Die Temperature and Porang (Amorphophallus mulleri B.) Flour on the Physicochemical Properties, Nutritional Value, Estimated Glycemic Index, and Sensory Evaluation of Brown Rice Snack by a Collet Extruder
DOI: 10.12982/CMJS.2025.003.

Cindytia Selvina Bernas, Sagar Pandappa Kalahal, Domas Galih Patria and Jenshinn Lin

Vol.52 No.1 (January 2025)
Research Article View: 1,929 Download: 385
Nitrogen Starvation for Increasing Lipid and Fatty Acid Methyl Ester on Euglena sp. Potential as Biojet Fuel
DOI: 10.12982/CMJS.2024.093.

Wulan Rahmani Akmal, Ersi Larasati, Renata Adaranyssa Egistha Putri, Tia Erfianti, Rejeki Siti Ferniah, Arief Budiman and Eko Agus Suyono

Vol.51 No.6 (November 2024)
Research Article View: 930 Download: 488
Microbiological and Biochemical Characterization, and Sensory Evaluation of Dragon Blood Tea Kombucha
DOI: 10.12982/CMJS.2024.088.

Niphawan Panti, Phatthanapong Therdtatha, Suttida Doungta, Supakan Saenkam, Phisit Seesuriyachan, Pornchai Rachtanapun and Kasirawat Sawangrat

Vol.51 No.6 (November 2024)
Research Article View: 1,680 Download: 1,115
Antimicrobial Metabolites from the Freshwater Fungus Tubeufia longihelicospora Strain GZCC 23-0405
DOI: 10.12982/CMJS.2024.053.

Lijuan Zhang, Jian Ma, Tianming Zhao, Meiyan Han, Dege Zheng, Ruvishika S. Jayawardena, Ausana Mapook and Yongzhong Lu

Vol.51 No.4 (July 2024)
Research Article View: 1,810 Download: 717
Effects of Selected Yeasts on the Chemical Profiles and Antioxidant Activity of Fermented Coffee Beans during the Aging Process
DOI: 10.12982/CMJS.2024.016.

Yi-Ting Chang, Pi-Hui Hsu, Mao-Che Chiu and Jui-Yu Chou

Vol.51 No.1 (January 2024)
Research Article View: 2,074 Download: 543
Evaluation of Alcoholic Extracts of Mucuna pruriens (L.) DC. Var. utilis for Antibacterial, Antioxidant and Cytotoxic Activities toward Human Cancer Cell Lines
DOI: 10.12982/CMJS.2023.045.

Kanokwan Jitpimai, Lukana Ngiwsara, Weeranuch Lang, Thanawan Panichpat, Ratchanee Mingma, Jisnuson Svasti and Jintanart Wongchawalit

Vol.50 No.5 (September 2023)
Research Article View: 2,760 Download: 1,178
Synthesis and Biological Evaluation of Sulfamoyl Carboxamide Derivatives from Sulfur-containing α-Amino acids
DOI: 10.12982/CMJS.2022.070.

Melford C. Egbujor, Uchechukwu C. Okoro, Attah S. Egu, Vivian I. Okonkwo, Sunday N. Okafor, Chigbundu N. Emeruwa, Pius I. Egwuatu, Odera R. Umeh, Mercy I. Eziafakaego, Ifeanyi S. Amasiatu and David C. Nwobodo

Vol.49 No.4 (July 2022)
Research Article View: 2,469 Download: 400
Determination of Both Total Phenolic Compound and Antioxidant Capacity of Herbal Teas Using Smartphone Digital Imaging
DOI: 10.12982/CMJS.2022.030.

Hau Van Nguyen, Jaroon Jakmunee, Napaporn Youngvises and Pakorn Preechaburana

Vol.49 No.2 (March 2022)
Research Article View: 2,042 Download: 1,452
Genetic Diversity Assessment Through Morphological, Biological, and Molecular Studies Among Thai Holy Basil Landraces and Commercial Cultivars
page: 1500 - 1510

Ponsit Sathapondecha and Sukhuman Whankaew

Vol.48 No.6 (November 2021)
Research Article View: 2,492 Download: 782
Antioxidant and Antiproliferative Properties of a Chinese Water Chestnut Extract and Its Biologically Active Isolated Compounds
page: 1036 - 1044

Jinfeng Yang, Myong Jo Kim, Weiling Chen, Yong Soo Kwon and Ji Hye Yoo

Vol.48 No.4 (July 2021)
Research Article View: 1,271 Download: 132
Investigation of Skin Whitening Property of Soybean Seed Protein; Anti-tyrosinase, Anti-inflammation and Antioxidant
page: 150 - 162

Anupong Joompang, Wisarut Payoungkiattikun, Jirayut Dansuk, Napat Nuramrum, Nisachon Jangpromma, Santi Phosri, Bancha Mahong and Sompong Klaynongsruang*

Vol.48 No.1 (January 2021)
Research Article View: 1,849 Download: 1,202
Synthesis, Characterization, Antimicrobial, Antioxidant Activities of Schiff Base and its Transition Metal Complexes
page: 1241 - 1254

Atta Ullah Khan*, Iqbal Hussain and Riaz Ullah

Vol.47 No.6 (November 2020)
Research Article View: 1,306 Download: 603
Antioxidant and Anti-inflammatory Activities of Ethanolic Extract from Hoya kerrii Craib
page: 912 - 925

Patcharawan Sittisart, Benjawan Dunkhunthod and Chokchai Chuea-nongthon

Vol.47 No.5 (September 2020)
Research Article View: 1,630 Download: 742
Antioxidant, Anti-tyrosinase, Anti-aging Potentialsand Safety of Arabica Coffee Cherry Extract
page: 930 - 945

Kanokwan Kiattisin*, Nutjeera Intasai, Nichcha Nitthikan, Thananya Nantarat, Kuan-Han Lee, Wei-Chao Lin, Shang-Chian Lue and Pimporn Leelapornpisid

Vol.46 No.5 (September 2019)
Research Article View: 1,428 Download: 660
Antioxidant and Anti-inflammatory Activities of the Siamese Crocodile (Crocodylus Siamensis) Hemoglobin Hydrolysate Derived from Trypsin and Papain Hydrolysis
page: 915 - 929

Jiraporn Lueangsakulthai, Nicholas Michael, Theeranan Temsiripong, Watcharee Khunkitti, Sompong Klaynongsruang, Nisachon Jangpromma*

Vol.46 No.5 (September 2019)
Research Article View: 1,109 Download: 534
Anti-inflammatory, Antioxidant Activities and Safety of Coffea arabica Leaf Extract for Alternative Cosmetic Ingredient
page: 284 - 294

Kanokwan Kiattisin, Nichcha Nitthikan, Worrapan Poomanee, Pimporn Leelapornpisid, Helmut Viernstein and Monika Mueller

Vol.46 No.2 (March 2019)
Research Article View: 1,127 Download: 1,020
Pharmaceutical and Cosmeceutical Biological Activities of Hemp (Cannabis sativa L var. sativa) Leaf and Seed Extracts
page: 180 - 195

Aranya Manosroi, Charinya Chankhampan, Bang-on Kietthanakorn, Warintorn Ruksiriwanich, Puxvadee Chaikul, Korawinwich Boonpisuttinant, Mathukorn Sainakham, Worapaka Manosroi, Theeraphong Tangjai and Jiradej Manosroi

Vol.46 No.2 (March 2019)
Research Article View: 1,972 Download: 661
Phytochemical Investigation and Antioxidant Properties of Different Extracts from Artabotrys harmandii Finet & Gagnep
page: 2338 - 2347

Wararut Bunchareon, Supaporn Pamok, Supap Saenphet and Kanokporn Saenphet

Vol.45 No.6 (September 2018)
Research Article View: 1,151 Download: 459
Comparative GC-MS Analysis, In-vitro Antioxidant and Antimicrobial Activities of the Essential Oils Isolated from the Peel of Omani Lime
page: 1782 - 1795

Amwaj Mohammed Al-Breiki, Huda Mubarak Al-Brashdi, Jamal Nasser Al-Sabahi and Shah Alam Khan

Vol.45 No.4 (July 2018)
Research Article View: 1,425 Download: 366
Chemometric Profiling of Clinacanthus nutans Leaves Possessing Antioxidant Activities using Ultraviolet-visible Spectrophotometry
page: 1519 - 1530

Hui Wen Chong, Khansa Rezaei, Bee Lynn Chew and Vuanghao Lim*

Vol.45 No.3 (May 2018)
Research Article View: 1,124 Download: 379
Phytochemical Constituents of Thai Dark Purple Glutinous Rice Bran Extract [Cultivar Luem Pua (Oryza sativa L.)]
page: 1383 - 1395

Pattawat Seekhaw, Sugunya Mahatheeranont, Phumon Sookwong, Suwaporn Luangkamin, Acharaporn Na Lampang Neonplab and Pakawan Puangsombat*

Vol.45 No.3 (May 2018)
Research Article View: 1,302 Download: 742
Antioxidant and Antimicrobial Properties of Polysaccharides from Rice Brans
page: 1372 - 1382

Siriluck Surin, Phisit Seesuriyachan, Prodpran Thakeow, SangGuan You and Yuthana Phimolsiripol*

Vol.45 No.3 (May 2018)
Research Article View: 1,257 Download: 447
Antioxidant Properties of Crocodylus siamensis Blood Components on H2O2-induced Human Skin Fibroblast Cells
page: 1359 - 1371

Nisachon Jangpromma, Khantheeranut Suttee, Santi Phosri, Tinnakorn Theansungnoen, Jiraporn Lueangsakulthai, Wisarut Payoungkiattikun, Sakda Daduang and Sompong Klaynongsruang*

Vol.45 No.3 (May 2018)
Research Article View: 1,302 Download: 492
Effects of Three Drying Treatments on the Polyphenol Content, Antioxidant and Antimicrobial Properties of Syzygium aromaticum Extract
page: 937 - 948

Suat-HianTan* and Md. Rezaul Karim

Vol.45 No.2 (March 2018)
Research Article View: 1,097 Download: 280
Phenolic Compounds and Antioxidant Activities of Four Edible Species During Seed Germination
page: 905 - 916

Arthitaya Kawee-ai, Pimpak Phumat, Siriporn Okonogi, Srikarnjana Klayraung and Phisit Seesuriyachan*

Vol.45 No.2 (March 2018)
Research Article View: 1,229 Download: 344
Antioxidant, Anti-tyrosinase and Immunomodulatory Activities of the Enzymatic Boiled Venus Clam Hydrolysate
page: 249 - 262

Chanutchamon Sutthiwanjampa and Sang Moo Kim

Vol.45 No.1 (January 2018)
Research Article View: 1,093 Download: 452
Comparative analysis of protein profiles of toxic and non-toxic Jatropha curcas latex
page: 1379 - 1391

Lucsame Gurnecka, Eleni Gentekakia, Janthima Jaresitthikunchaib, Teerawit Waratrujiwonga, Sittiruk R

Vol.44 No.4 (October 2017)
Research Article View: 972 Download: 531
In vitro Anti-aging Activities of Crocodile (Crocodylus siamensis) Blood Extracts
page: 1334 - 1346

Jiradej Manosroi, Charinya Chankhampan, Worapaka Manosroi and Aranya Manosroi*

Vol.44 No.4 (October 2017)
Research Article View: 1,247 Download: 341
Antioxidant, Total Phenolics and Total Flavonoid Content of the Aqueous Extract of Caesalpinia bonducella Seeds
page: 929 - 938

Shruti Shukla* and Archana Mehta

Vol.44 No.3 (July 2017)
Research Article View: 1,197 Download: 477
Innovating Botanical Extraction through Application of Microwaves for the Efficient Extraction of Ursolic Acid from Ocimum sanctum Leaves
page: 869 - 880

Rajendra Mehta, Raj Kumar, Roshni Tandey and Vivekananda Mandal*

Vol.44 No.3 (July 2017)
Research Article View: 1,058 Download: 308
Chemical Profiles and Antimicrobial Activities of Thai Propolis Collected from Apis mellifera
page: 438 - 448

Sirikarn Sanpa [a,b], Milena Popova [c], Tawee Tunkasiri [d], Sukum Eitssayeam [d], Vassya Bankova [

Vol.44 No.2 (April 2017)
Research Article View: 1,973 Download: 474
Ultrasonic Extraction, Antioxidant and Anti-glycation Activities of Polysaccharides from Gynura divaricata Leaves
page: 144 - 156

Pawinee Deetae*[a, e], Kwanrudee Tseng [a], Chanathinart Pasuphan [a], Atikorn Panya [b], Pawadee Methacanon [c], Waranya Temthawee [a] and Manop Suphantharika [d]

Vol.44 No.1 (JANUARY 2017)
Research Article View: 2,375 Download: 415
Photo-remediation of Phenanthrene Contaminated Soil under Visible Light Irradiation
page: 845 - 850

Chonlada Dechakiatkrai Theerakarunwong*[a], and Sukon Phanichphant[b]

Vol.43 No.4 (JULY 2016)
Research Article View: 1,000 Download: 356
Antioxidant Compounds and Activities in Selected Fresh and Blanched Vegetables from Northeastern Thailand
page: 834 - 844

Thidarat Somdee*[a], Udomsak Mahaweerawat [a], Methin Phadungkit [b] and Suneerat Yangyuen [a]

Vol.43 No.4 (JULY 2016)
Research Article View: 1,079 Download: 293
Synthesis, Characterization and Antioxidant Activity of 2-Halobenzoyl Thiourea bearing α- and β-Alanine
page: 578 - 584

Nurziana Ngah*, Nor Azanita Mohamed, and Deny Susanti Darnis

Vol.43 No.3 (APRIL 2016)
Research Article View: 1,004 Download: 319
Phytochemical Constituents with Antimicrobial and Antioxidant Activities from Xylia xylocarpa (Roxb.) Taub. Sawdust Extracts
page: 11 - 21

Pattarawadee Sumthong Nakmee* [a], Soontree Khuntong [a] and Nitra Nuengchamnong [b]

Vol.43 No.1 (JANUARY 2016)
Research Article View: 1,157 Download: 424
Identificationof Bioactive Moleculesfrom Thai Centipede, Scolopendra subspinipes dehaani, Venom
page: 1 - 10

Muchalin Meunchan, Nunthawun Uawonggul, Praroonkorn Incamnoi, Sophida Sukprasert, Prapenpuksiri Rungsa, Theerasak Somdee, Sittiruk Roytrakul, Sompong Thammasirirak and Sakda Daduang*

Vol.43 No.1 (JANUARY 2016)
Research Article View: 1,111 Download: 309
Fatty Acid, Essential Oil and Phenolic Compositions of Alcea pallida and Alcea apterocarpa with Antioxidant, Anticholinesterase and Antimicrobial Activities
page: 89 - 99

Abdulselam Ertas*[a,b], Mehmet Boga [b,c], Isil Gazioglu [d], Yeter Yesil [e] , Nesrin Hasimi [f], Cumali Ozaslan [g], Hasibe Yilmaz[h], Muammer Kaplan[j]

Vol.43 No.1 (JANUARY 2016)
Research Article View: 1,119 Download: 380
Prediction of Antioxidant Capacity of Thai Vegetable Extracts by Infrared Spectroscopy
page: 657 - 668

Trakul Prommajak, Sang Moo Kim, Cheol-Ho Pan, Sang Min Kim, Suthat Surawang, Nithiya

Vol.42 No.3 (JULY 2015)
Research Article View: 1,152 Download: 334
Plasma Assisted Immobilization of TiO2 nanoparticles onto PLA Surface to Promote the Antimicrobial Activity
page: 1361 - 1374

Chonlada Theerakarunwong*[a], Somruthai Tunma[b] and Dheerawan Boonyawan[c]

Vol.41 No.5/2 (OCTOBER 2014)
Research Article View: 963 Download: 260
Betel-like-scented Piper Plants as Diverse Sources of Industrial and Medicinal Aromatic Chemicals
page: 1171 - 1181

Arisa Sanubol [a], Arunrat Chaveerach*[a], Runglawan Sudmoon [a], Tawatchai Tanee [b], Kowit Noikotr

Vol.41 No.5/1 (OCTOBER 2014)
Research Article View: 1,774 Download: 310
Supercritical Fluid Extraction and Gas Chromatographic-Mass Spectrometric Analysis of Terpenoids in Fresh Kaffir Lime Leaf Oil†
page: 240 - 247

Orranuch Norkaew[a], Kitsada Pitija[a], Patcharee Pripdeevech[b], Phumon Sookwong[a], and Sugunya Wo

Vol.40 No.2 (APRIL 2013)
Research Article View: 968 Download: 451
In vitro INHIBITION OF LIPID PEROXIDATION AND THE ANTIOXIDANT SYSTEM OF ENDOPHYTIC FUNGI FROM THAI MEDICINAL PLANTS
page: 429 - 444

Teerayut Theantana [a,b], Duangta Kanjanapothi [c], Saisamorn Lumyong* [b]

Vol.39 No.3 (JULY 2012)
Research Article View: 1,104 Download: 294
Comparative Analysis of Aqueous Extracts of Amaranth and Coriander in Scavenging Free Radical Activity and Protection of DNA against Oxidative Damage
page: 560 - 571

Asmita Dutta and Mukesh Singh

Vol.38 No.4 (OCTOBER 2011)
Research Article View: 1,079 Download: 410
Antioxidant Capacity of Broccoli Seeds Grown in Thailand
page: 117 - 122

Sarunya Chuanphongpanich* [a], Maitree Suttajit [b], Sukon Phanichphant [c Duang Buddhasukh [c]

Vol.33 No.1 (JANUARY 2006)
Research Article View: 1,074 Download: 369
Extraction of Phenolic Compounds from Fruits of Bitter Melon (Momordica charantia ) with Subcritical Water Extraction and Antioxidant Activities of These Extracts
page: 123 - 130

Parichat Budrat and Artiwan Shotipruk

Vol.35 No.1 (JANUARY 2008)
Research Article View: 1,158 Download: 680
Red Yeast Rice Prepared from Thai Glutinous Rice and the Antioxidant Activities
page: 42 - 49

Em-on Chairote, Griangsak Chairote, and Saisamorn Lumyong

Vol.36 No.1 (JANUARY 2009)
Research Article View: 1,251 Download: 375
GC-MS Analysis of Fatty Acids in Thai Durian Aril
page: 155 - 158

Weerachai Phutdhawong* [a], Sumittra Kaewkong [a] and Duang Buddhasukh [b]

Vol.32 No.2 (MAY 2005)
Short Communication View: 1,041 Download: 724
Screening of Antioxidants from Some Thai Vegetables and Herbs
page: 1 - 5

Anchana Chanwitheesuk, Nuansri Rakariyatham*, Aphiwat Teerawutgulrag and Teerapol Wongchanapiboon

Vol.29 No.1 (APRIL 2002)
Opinion View: 1,245 Download: 370
Outline
Figures