Chiang Mai Journal of Science

Print ISSN: 0125-2526 | eISSN : 2465-3845

2,467
Articles
Q3 1.0
Impact Factor
Q2 1.6
CiteScore
7 days
Avg. First Decision
Outline
Figures and Tables
ARTICLE METRICS
Views 1,686
Downloads 693

Diversity of Endophytic Fungi Isolated from Thai Medicinal Plants (Casearia grewiifolia) in Khon Kaen, Thailand, and their Bioactive Compounds

Natanong Yodsing, Somdej Kanokmedhakul, Wiyada Mongkolthanaruk, Tadanori Aimi, Totsaporn Srisapoomi and Sophon Boonlue
* Author for corresponding; e-mail address: bsopho@kku.ac.th
Volume: Vol.45 No.1 (January 2018)
Research Article
DOI:
Received: 20 December 2016, Revised: -, Accepted: 20 March 2017, Published: -

Citation: Yodsing N., Kanokmedhakul S., Mongkolthanaruk W., Aimi T., Srisapoomi T. and Boonlue S., Diversity of Endophytic Fungi Isolated from Thai Medicinal Plants (Casearia grewiifolia) in Khon Kaen, Thailand, and their Bioactive Compounds, Chiang Mai Journal of Science, 2018; 45(1): 45-59.

Abstract

Endophytic fungi were isolated from Casearia grewiifolia and evaluated for antimicrobial activity. Seven different fungal taxa, including Aspergillus candidus, Neosartorya fischeri, N. tatenoi, Paecilomyces herbarum, Phomopsis sp., Xylaria berteri, and X. feejeensis were the  dominant endophytes recovered in this study. They all  grouped into the species belonging to Ascomycota with limited morphological and molecular data. Phomopsis sp. had the highest colonization frequency found in the plant. Colonization was greater during summer season in samples taken from leaves. The similarity indices between leaf and twig were 0.571 for Jaccard’s and 0.727 for the Sorenson index, respectively. Neosartorya spp. showed antimicrobial activity against several pathogenic microorganisms. Among endophytic fungi, N. fischeri KK-KP-P2 produced the most effective extra-cellular metabolite, which had broad spectrum activity against 10 different species of tested pathogens. Interestingly, this fungal isolate inhibited the growth of Fusarium oxysporum f. sp. lycopersici, well with 56.92% of radial growth inhibition in dual culture test. The major bioactive compound from N. fischeri KK-KP-P2 was isolated by chromatographic techniques and identified by spectroscopic methods as a sesquiterpenoid. This compound had the great antimicrobial activity against many pathogens and clearly affected on bacterial cell morphology when observed by scanning electron microscopy. Our study infers that Thai medicinal plants are able to provide a wide variety of endophytes that might be a potential source of novel bioactive compounds.

Keywords: Antimicrobial activity, Diversity, Endophytic fungi, susquiterpenoid, Thai medicinal plant

Related Articles

Edaphic Factors Drive the Diversity and Abundance of AMF Associated with Cenchrus ciliaris L. Growing in Different Arid Rangelands of Saudi Arabia
DOI: 10.12982/CMJS.2026.071.

Jahangir A. Malik, Basharat A. Dar*, Abdulaziz A. Alqarawi, Abdulaziz M. Assaeed, Fahad Alotaibi* and Muhammad M. Habib

Vol.53 No.4 (July 2026)
Research Article View: 587 Download: 103
Biodiversity of Aquatic Insects and Water Quality Parameters in Thac Bac Stream, Tam Dao National Park, Vietnam
DOI: 10.12982/CMJS.2024.092.

Hieu Van Nguyen, Cuong Van Duong, Nattawut Sareein, Christine Jewel C. Uy-Yabut, Anh Duc Tran and Vinh Van Nguyen

Vol.51 No.6 (November 2024)
Research Article View: 1,683 Download: 584
Diversity and Abundance of Non-Geniculate Coralline Algae (NGCA) in Different Reef Conditions and Depth Zones
DOI: 10.12982/CMJS.2024.050.

Kattika Pattarach, Shao-Lun Liu and Jaruwan Mayakun

Vol.51 No.3 (May 2024)
Research Article View: 1,686 Download: 342
Diversity of Yeasts from Food Waste and Their Potential for Thermotolerance and Hydrolytic Enzyme Production
DOI: 10.12982/CMJS.2024.012.

Jemisha Dudhat, Napapohn Kajadpai, Jirameth Angchuan, Varunya Sakpuntoon and Nantana Srisuk

Vol.51 No.1 (January 2024)
Research Article View: 2,309 Download: 904
Two Novel Records of Agaricus (Agaricaceae, Agaricales) from Southwest China
DOI: 10.12982/CMJS.2023.061.

Wen-Hua Lu, Saowaluck Tibpromma, Jaturong Kumla, Dong-Qin Dai, Samantha C. Karunarathna and Xiao-Yan Wang

Vol.50 No.6 (November 2023)
Research Article View: 2,206 Download: 514
New Species of Cercosporoid on Mango in Thailand
DOI: 10.12982/CMJS.2022.053.

Nisachon Tamakaew, Anuruddha Karunarathna, Parichad Pakdeeniti, Patchareeya Withee, Chanokned Senwanna, Sukanya Haituk and Ratchadawan Cheewangkoon

Vol.49 No.3 (Special Issue II : May 2022)
Research Article View: 2,102 Download: 1,689
Two Pleurotus Species (Pleurotaceae) From Lao People’s Democratic Republic
page: 1224 - 1235

Monthien Phonemany, Olivier Raspé, Phongeun Sysouphanthong, Allen Grace T. Niego, Naritsada Thongklang, Boontiya Chuankid and Kevin D. Hyde

Vol.48 No.5 (September 2021)
Research Article View: 2,628 Download: 546
Antimicrobial Potential of Fungi Isolated from Soils of Dry Dipterocarp Forest in Northeast Thailand
page: 793 - 807

Panjamaphon Chanthasena, Watsana Penkhrue, Phimpha Khowangklang, Pishyaporn Sritangos and Nawarat Nantapong

Vol.48 No.3 (Special Issue I : May 2021)
Research Article View: 1,284 Download: 415
Actinomycins Produced by Streptomyces lichenis LCR6-01T and its Antibacterial Activity
page: 864 - 871

Pawina Kanchanasin, Patcharin Saeng-in, Takuji Nakashima, Hirotaka Matsuo, Yōko Takahashi and Somboon Tanasupawat

Vol.47 No.5 (September 2020)
Research Article View: 1,385 Download: 1,618
Isolation and Diversity of Actinomycetes from Sediments of Different Depths Between 34 m and 3,235 m in South China Sea
page: 1595 - 1609

Manita Kamjam, Qinqyi Xie, Zixin Deng and Kui Hong

Vol.45 No.4 (July 2018)
Research Article View: 1,759 Download: 445
Diversity and Plant Growth Promoting Activities of Actinomycetes from Mangroves
page: 1210 - 1223

Paweena Suksaard, Wasu Pathom-aree and Kannika Duangmal

Vol.44 No.4 (October 2017)
Research Article View: 2,002 Download: 592
Diversity of Polychaetes in Mangrove Forest, Prasae Estuary, Rayong Province, Thailand
page: 816 - 823

Somtawin Jaritkhuan*, Pongrat Damrongrojwattana, Benchawan Chewprecha and Vichaya Kunbou

Vol.44 No.3 (July 2017)
Research Article View: 1,605 Download: 561
Antioxidant and Antimicrobial Properties of a Brown Alga Scytosiphon lomentaria
page: 595 - 604

Xiao Juan Xu, Yu Zhang, Hong Lin, Chao Kang, Xiao Ting Fu*

Vol.44 No.2 (April 2017)
Research Article View: 1,279 Download: 290
In vitro Antimicrobial and Cytotoxic Activities of Mangrove Actinomycetes from Eastern Thailand
page: 322 - 337

Janpen Tangjitjaroenkun [a], Rungnapa Tangchitcharoenkhul [b], Waraporn Yahayo [c] and Roongtawan Su

Vol.44 No.2 (April 2017)
Research Article View: 1,211 Download: 240
The genus Hyboella Hancock in Thailand (Orthoptera: Tetrigidae: Metrodorinae)
page: 125 - 131

Ling-sheng Zha, Ting-chi Wen, Ji-chuan Kang*, Kevin D. Hyde

Vol.44 No.1 (JANUARY 2017)
Research Article View: 1,768 Download: 363
An Investigation on North Adana (Turkey) Myxomycetes
page: 54 - 67

Hayri Baba* [a], Murat Zmre [a], Muharrem Gelen [a]

Vol.43 No.1 (JANUARY 2016)
Research Article View: 1,684 Download: 335
Synthesis, Characterization and Antimicrobial Evaluation of Transition Metal Complexes of Monodentate 2-(Substituted Phenyl)-1H-benzo[d]imidazoles
page: 216 - 227

Minaxi S Maru and Manish K Shah

Vol.42 No.1 (JANUARY 2015)
Research Article View: 1,185 Download: 301
Marine Derived Fungi of Peninsular Malaysia-a Biochemical Perspective
page: 894 - 909

Audra Shaleena Paliany, Yasodha Sivasothy, Khalijah Awang, Mohammed Rizman-Idid and Siti Aisyah Alia

Vol.41 No.4 (SPECIAL ISSUE 1)
Research Article View: 1,743 Download: 253
Phylogenetic Diversity of Russula from Xiaozhongdian, Yunnan, China, Inferred from Internal Transcribed Spacer Sequence Data
page: 811 - 821

Jiayu Guo, Samantha C. Karunarathna, Peter E. Mortimer*, Jianchu Xu and Kevin D. Hyde

Vol.41 No.4 (SPECIAL ISSUE 1)
Research Article View: 1,695 Download: 418
Distribution and Taxonomy of Genus Aconitum in Kashmir: Potent Medicinal Resource of Himalayan Valley
page: 173 - 186

Neelofar Jabeen, Mohammad l Kozgar, Ghulam H. Dar, Abdul S. Shawl and Samiullah Khan

Vol.40 No.2 (APRIL 2013)
Research Article View: 1,684 Download: 284
Antimicrobial and Antioxidant Activities of Methanol, Dichloromethane and Ethyl Acetate Extracts of Scutellaria lindbergii Rech.f.
page: 49 - 59

Bibi Sedigheh Fazly-Bazzaz *[a], Atefeh Arab [b], Seyed Ahmad Emami [c], Javad Asili [c], Mohamad Ha

Vol.40 No.1 (JANUARY 2013)
Research Article View: 1,286 Download: 344
Screening of Volcanic Cave Actinomycetes for Antimicrobial Activity Against Paenibacillus larvae, A Honey Bee Pathogen
page: 26 - 33

Silvia Kay [a], Wasu Pathom-aree [b], and Naowarat Cheeptham*[a]

Vol.40 No.1 (JANUARY 2013)
Research Article View: 1,187 Download: 375
Evaluation of Effective Entomopathogenic Fungi to Fruit Fly Pupa, Bactrocera spp., and Their Antimicrobial Activity
page: 464 - 477

Thet Thet Mar and Saisamorn Lumyong*

Vol.39 No.3 (JULY 2012)
Research Article View: 1,099 Download: 300
In vitro INHIBITION OF LIPID PEROXIDATION AND THE ANTIOXIDANT SYSTEM OF ENDOPHYTIC FUNGI FROM THAI MEDICINAL PLANTS
page: 429 - 444

Teerayut Theantana [a,b], Duangta Kanjanapothi [c], Saisamorn Lumyong* [b]

Vol.39 No.3 (JULY 2012)
Research Article View: 1,309 Download: 302
Diversity of Aquatic Insects and Their Functional Feeding Group from Anthropogenically Disturbed Streams in Mae Sot District, Tak Province, Thailand
page: 399 - 409

Isara Thanee and Chitchol Phalaraksh*

Vol.39 No.3 (JULY 2012)
Research Article View: 1,849 Download: 390
Diversity of Endophytic Fungi Associated with Cinnamomum bejolghota (Lauraceae) in Northern Thailand
page: 389 - 398

Nakarin Suwannarach [a], Boonsom Bussaban [a], Wipornpan Nuangmek [b], Eric H.C. McKenzie [c], Kevin

Vol.39 No.3 (JULY 2012)
Research Article View: 1,145 Download: 380
Diversity of Figs and Their Pollinators in Chiang Mai Province, Thailand
page: 638 - 647

Yaowanit Tarachai, Prachaval Sukumalanand, Prasit Wangpakapattanawong, Stephen G. Compton and

Vol.38 No.4 (OCTOBER 2011)
Research Article View: 1,862 Download: 330
Variation Under Nature: A Sesquicentennial DNA Barcoding Perspective
page: 188 - 199

J. William O. Ballard, Louise Puslednik, Jonci N. Wolff, and Richard C. Russell

Vol.36 No.2 (MAY 2009)
Short Communication View: 1,801 Download: 360
Inhibitory Effect of Thermotolerant Lactic Acid Bacteria on the Growth of Bacillus cereus, Staphylococcus aureus, Salmonella enteritidis and Vibrio parahaemolyticus
page: 119 - 124

Atchara Lapmak [a], Sumana Kumpai [b] and Abhinya Plikomol*[b]

Vol.28 No.2 (DECEMBER 2001)
Opinion View: 1,301 Download: 290
Outline
Figures