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Actinomycins Produced by Streptomyces lichenis LCR6-01T and its Antibacterial Activity
Paper Type  |
Contributed Paper |
Title |
Actinomycins Produced by Streptomyces lichenis LCR6-01T and its Antibacterial Activity |
Author |
Pawina Kanchanasin, Patcharin Saeng-in, Takuji Nakashima, Hirotaka Matsuo, Yōko Takahashi and Somboon Tanasupawat |
Email |
Somboon.T@chula.ac.th |
|
Abstract: A new actinomycete species, Streptomyces lichenis LCR6-01T was isolated from lichen collected in Chiang Rai province, Thailand. On the course of screening for antimicrobial activity, the culture broth of strain LCR6-01T exhibited antibacterial activity against Bacillus subtilis ATCC 6633, Kocuria rhizophila ATCC 9341, Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 25922 (inhibition zone 14.7 ± 0.6 - 23.0 ± 0.9 mm). The culture extracts analyzed by liquid chromatographyelectrospray ionization-mass spectrometry (LC-ESI-MS) and the physicochemical properties of secondary metabolites were searched in database. The antibacterial agents were detected as actinomycins which contained 3 analogs of Au7a, D, and D 43β. |
|
Start & End Page |
864 - 871 |
Received Date |
2020-04-16 |
Revised Date |
|
Accepted Date |
2020-06-10 |
Full Text |
Download |
File Supplemental |
Download Supplemental |
Keyword |
Streptomyces lichenis, antimicrobial activity, actinomycin, mass spectrometry |
Volume |
Vol.47 No.5 (September 2020) |
DOI |
|
Citation |
Kanchanasin P., Saeng-in P., Nakashima T., Matsuo H., Takahashi Y. and Tanasupawat S., Actinomycins Produced by Streptomyces lichenis LCR6-01T and its Antibacterial Activity, Chiang Mai J. Sci., 2020; 47(5): 864-871. |
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