Chiang Mai Journal of Science

Print ISSN: 0125-2526 | eISSN : 2465-3845

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Nickel-catalyzed One-pot, Three-component Synthesis of 3,4-Disubstituted Isoxazole-5(4H)-ones in Aqueous Medium

Hamzeh Kiyani* and Heshmat Allah Samimi
* Author for corresponding; e-mail address: hkiyani@du.ac.ir
Volume: Vol.44 No.3 (July 2017)
Research Article
DOI:
Received: 13 March 2015, Revised: -, Accepted: 17 May 2015, Published: -

Citation: Kiyani H. and Samimi H.A., Nickel-catalyzed One-pot, Three-component Synthesis of 3,4-Disubstituted Isoxazole-5(4H)-ones in Aqueous Medium, Chiang Mai Journal of Science, 2017; 44(3): 1011-1021.

Abstract

An efficient and simple cyclocondensation approach for the one-pot, three-component synthesis of 3,4-disubtituted isoxazole-5(4H)-ones has been described. This three-component reaction was completed easily and cleanly to give corresponding isoxazoles in the presence of Ni(OAc)2.H2O as the catalyst. The reaction was implemented in aqueous media at room temoerature and the corresponding heterocyclic were obtained in good to high yields. The present work offers notable advantages, including easy work-up, simple procedure, mild condition, and no use of organic solvents.

Keywords: 3,4-disubstituted isoxazole-5(4H)-ones, Ni(OAc)2.H2O, water, three-component synthesis, B-oxoesters

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Vulnerability Assessment of Groundwation Resources, Chinag Mai Basin
page: 73 - 78

Terdsak Subtavewung, and Fongsaward S. Singharajwarapan

Vol.34 No.1 (JANUARY 2007)
Research Article View: 907 Download: 768
Effect of Nitrogen and Phosphorus on the Dynamics of Blue-green Algae in the Mae Ngat Somboonchol Reservoir, Chiang Mai, Thailand
page: 253 - 268

Khajornkiat Saeton, and Siripen Traichaiyaporn

Vol.34 No.2 (MAY 2007)
Research Article View: 901 Download: 268
Estimation of Water Content in PEM Fuel Cell
page: 212 - 220

Chinnavat Thawornkuno and Chanin Panjapornpon

Vol.35 No.1 (JANUARY 2008)
Research Article View: 946 Download: 978
Extraction of Phenolic Compounds from Fruits of Bitter Melon (Momordica charantia ) with Subcritical Water Extraction and Antioxidant Activities of These Extracts
page: 123 - 130

Parichat Budrat and Artiwan Shotipruk

Vol.35 No.1 (JANUARY 2008)
Research Article View: 1,059 Download: 677
Value Added Products from By-products of Rice Bran Oil Processing
page: 116 - 122

Wasinee Kaewboonnum, Ketmanee Wachararuji and Artiwan Shotipruk

Vol.35 No.1 (JANUARY 2008)
Research Article View: 1,022 Download: 262
Subcritical Water Extraction of Polyphenolic Compounds from Terminalia chebula Fruits
page: 103 - 108

Rangsriwong P., Rangkadilok N., and Shotipruk A

Vol.35 No.1 (JANUARY 2008)
Research Article View: 944 Download: 267
Biosorption of Lead (II) and Copper (II) from Aqueous Solution
page: 69 - 81

Woranart Jonglertjunya

Vol.35 No.1 (JANUARY 2008)
Research Article View: 942 Download: 294
Developing Indicators for Floodplain Wetlands: Managing Water in Agricultural Landscapes
page: 224 - 235

Kim Jenkins, Richard Kingsford, and Darren Ryder

Vol.36 No.2 (MAY 2009)
Short Communication View: 921 Download: 375
Treatment of Fermented Fish Production Wastewater by Constructed Wetland System in Thailand
page: 149 - 157

Suwasa Kantawanichkul, Seni Karnchanawong, and Shuh Ren Jing

Vol.36 No.2 (MAY 2009)
Short Communication View: 1,040 Download: 304
Cathodic Stripping Voltammetric Procedure for Determination of Some Inorganic Arsenic Species in Water, Soil and Ores Samples
page: 369 - 383

Jaroon Junsomboon, Ponlayuth Sooksamiti, Kate Grudpan, Somchai Lapanantnoppakhun, Prasak Thavornyuth

Vol.36 No.3 (SEPTEMBER 2009)
Research Article View: 954 Download: 248
Calculation of Weighted Averages Approach for the Estimation of Ping Tolerance Values
page: 151 - 159

Somyot Silalom, James L. Carter, and Porntip Chantaramongkol

Vol.37 No.1 (JANUARY 2010)
Research Article View: 926 Download: 249
Aggregation and Pedogenesis of Seasonally Inundated Soils of a Tropical Watershed
page: 74 - 84

Emmanuel U. Onweremadu, Ogochukwu P. Izuogu, and Frank O.R. Akamigbo

Vol.37 No.1 (JANUARY 2010)
Research Article View: 971 Download: 307
Concentrations of Arsenic in Water, Soil, Hair, and Biological Samples in Hizla, Bangladesh
page: 7 - 13

Abu Sayed Md. Kamal* and Preeda Parkpian

Vol.29 No.1 (APRIL 2002)
Research Article View: 935 Download: 313
Fifty One New Record Species of Freshwater Diatoms in Thailand
page: 97 - 112

Trai Pekthong and Yuwadee Peerapornpisal

Vol.28 No.2 (DECEMBER 2001)
Opinion View: 900 Download: 282
Solid Phase Extraction of Carbamate and Organochlorine Pesticides in Water
page: 9 - 15

Wanna Kanchanamayoon, Sirichai Hathongkam and Amnat Laothong

Vol.28 No.1 (JUNE 2001)
Opinion View: 919 Download: 508
Benthic Macroinvertebrates Diversity and Water Quality of Some Main Wetlands in Chiang Mai-Lamphun Basin
page: 102 - 113

Weerasak Roongruangwongse [a], Pongpor Asnachinda [b] and Wanchai Sonthichai [a]

Vol.27 No.2 (DECEMBER 2000)
Opinion View: 1,061 Download: 265
Population Dynamics of the Green-Lipped Mussel, Perna viridis from the Offshore Waters of Naf River Coast, Bangladesh
page: 344 - 354

Mohammed A.A. Khan, Zaini B. Assim, and Norhadi Ismail

Vol.37 No.2 (MAY 2010)
Research Article View: 954 Download: 397
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