Antioxidant and Anti-inflammatory Activities of Brown Marine Alga, Padina minor Yamada
Yuwadee Peerapornpisal, Doungporn Amornlerdpison, Utan Jamjai, Tawat Taesotikul, Yanee Pongpaibul,* Author for corresponding; e-mail address: doung_fishtech@hotmail.com
Volume :Vol.37 No.3 (SEPTEMBER 2010)
Research Article
DOI:
Received: 29 June 2009, Revised: -, Accepted: 21 May 2010, Published: -
Citation: Peerapornpisal Y., Amornlerdpison D., Jamjai U., Taesotikul T. and Pongpaibul Y., Antioxidant and Anti-inflammatory Activities of Brown Marine Alga, Padina minor Yamada, Chiang Mai Journal of Science, 2010; 37(3): 507-516.
Abstract
Padina minor of the Gulf of Thailand and the Andaman Sea. The aqueous extract of showed antioxidant activity when tested in superoxide and hydroxyl radical scavenging, metal chelating and reducing capacity assays. Although the concentrations of Aq activity were much higher than that of standard drugs when tested in various assays, their maximal effects were approximately the same. Topical application of Aq. could lessen the ear edema induced by ethyl phenylpropiolate (EPP), suggesting it possesses an anti-inflammatory activity. Interestingly, safety of the Aq. and a cosmeceutical were demonstrated according to the acute toxicity tests in rats and the irritation tests in rabbits, respectively. No signs of acute toxicity and skin irritation were observed. The findings therefore provide the evidence to substantiate the nutraceutical and cosmeceutical potential of Yamada is a brown marine alga found in abundance at the coastal areaP. minor (Aq. P)P. for antioxidantP on the rat earP to be used as a nutraceuticalP. minor.