Journal Volumes


Visitors
ALL : 2,335,316
TODAY : 6,570
ONLINE : 412

  JOURNAL DETAIL



Enhancement of Mycelial Biomass Production and Bioactive Properties Related to Cosmeceuticals of Calocybe indica (Milky Mushroom) by Optimization of Submerged Culture Conditions


Paper Type 
Contributed Paper
Title 
Enhancement of Mycelial Biomass Production and Bioactive Properties Related to Cosmeceuticals of Calocybe indica (Milky Mushroom) by Optimization of Submerged Culture Conditions
Author 
Natthawadee Vajrobol, Weerasak Taengphan and Churapa Teerapatsakul
Email 
fscicpt@ku.ac.th
Abstract:

     Calocybe indica or milky mushroom grown in submerged culture was investigated as a new source of antioxidants and anti-collagenase substances, and for its ability to inhibit three bacteria that trigger inflammatory acne, Cutibacterium acnes, Staphylococcus epidermidis, and S. aureus. To facilitate C. indica submerged cultivation and achieve high productivity, a three-level four-factor Box-Behnken design was utilized to find the optimal culture conditions for its mycelial biomass production. The model estimated the optimal conditions as 30 °C, a medium pH of 5.9, and incubation for 14 days under static culture, with results verifi ed by validation experiments. The optimal conditions gave mycelial biomass of 7.12 g/L, which is 5-fold higher than the original condition. This statistical method facilitated rapid identification and integration of key factors for C. indica high mycelial biomass production with significantly improved cosmeceutical properties in terms of antioxidant and antibacterial activities against acne-causing bacteria, especially C. acnes at 19-fold and 18-fold, respectively, compared to the original condition. An ethanolic extract derived from C. indica mycelia was nontoxic to human skin keratinocytes (HaCaT). These diverse functionalities indicate that the mycelial extract of C. indica may represent a promising source of bioactive substances for cosmeceutical applications.

Article ID
e2024075
Received Date 
2024-05-19
Revised Date 
2024-07-24
Accepted Date 
2024-07-25
Full Text 
  Download
Keyword 
Box-Behnken design, Calocybe indica, cosmeceutical, mushroom, submerged culture
Volume 
Vol.51 No.5 (September 2024)
DOI 
https://doi.org/10.12982/CMJS.2024.075
Citation 
Vajrobol N., Taengphan W. and Teerapatsakul C., Enhancement of Mycelial Biomass Production and Bioactive Properties Related to Cosmeceuticals of Calocybe indica (Milky Mushroom) by Optimization of Submerged Culture Conditions, Chiang Mai J. Sci., 2024; 51(5): e2024075. DOI 10.12982/CMJS.2024.075.
SDGs
View:450 Download:242

  RELATED ARTICLE

Comparative Structural Analysis of The Homeodomain Protein in the Bipolar Basidiomycete, Mycoleptodonoides aitchisonii (Bunaharitake)
Article ID: e2024014
Author:Weitong Zhang, Rini Riffiani, Kozue Sotome, Takayuki Wada, Norihiro Shimomura, Sophon Boonlue and Tadanori Aimi
Vol.51 No.1 (January 2024) View: 411 Download:259
Two Novel Records of Agaricus (Agaricaceae, Agaricales) from Southwest China
Article ID: e2023061
Author:Wen-Hua Lu, Saowaluck Tibpromma, Jaturong Kumla, Dong-Qin Dai, Samantha C. Karunarathna and Xiao-Yan Wang
Vol.50 No.6 (November 2023) View: 555 Download:277
Preliminary Characterization of Mucus Crude Extracts from Mushroom Phallus indusiatus
page: 194 - 204
Author:Thanyarat Saejung, Sarote Nitsawang and Patchara Punyamoonwongsa
Vol.49 No.1 (Special Issue I : Jan 2022) View: 793 Download:589
Nutritional Aspects of Three Termitomyces and Four Other Wild Edible Mushroom Species from Sri Lanka
page: 1236 - 1246
Author:Niranjan W. Gunasekara, Chandrika M. Nanayakkara, Samantha C. Karunarathna and Ravi L.C. Wijesundera
Vol.48 No.5 (September 2021) View: 802 Download:493
Development of a Novel Biomixture for Pesticide Degradation and Detoxification in Vietnam
page: 1021 - 1035
Author:Le Van Thien, Dao Van Huy and Ngo Thi Tuong Chau
Vol.48 No.4 (July 2021) View: 752 Download:304
Prescreening of Ligninolytic Enzyme-Producing Edible White-Rot Fungi
page: 808 - 826
Author:Charuwan Chuaseeharonnachai, Kanthawut Boonmee, Juthamas Suwanprateep, Sayanh Somrithipol, Natapol Pornputtapong and Nattawut Boonyuen
Vol.48 No.3 (Special Issue I : May 2021) View: 752 Download:452
Mushrooms: Splendid Gifts for the Cosmetic Industry
page: 699 - 725
Author:Kanaporn Sujarit, Nakarin Suwannarach, Jaturong Kumla and Thanasak Lomthong
Vol.48 No.3 (Special Issue I : May 2021) View: 1,286 Download:1,594
SDGs:
A Challenge for Mushroom Growers: Daldinia eschscholtzii Associated with Oyster Mushroom Growing Substrate
page: 774 - 786
Author:Achala J. Gajanayake, Milan C. Samarakoon, Digvijayini Bundhun, Ruvishika S. Jayawardena, Thatsanee Luangharn and Kevin D. Hyde
Vol.48 No.3 (Special Issue I : May 2021) View: 763 Download:431
SDGs:
Diversity and Molecular Phylogeny of Some Boletes from Three Conserved Forests in Chiang Mai, with Four New Records (Chiua viridula, Neoboletus obscureumbrinus, Parvixerocomus pseudoaokii and Xerocomus nigromaculatus) of Thailand
page: 867 - 883
Author:Sutheera Thongkantha, Sulichet Thongklam, Eric H.C. McKenzie, Saisamorn Lumyong, Wasu Pathom-aree and Boonsom Bussaban
Vol.48 No.3 (Special Issue I : May 2021) View: 762 Download:108
SDGs:
Anti-aging Cosmeceutical Product Containing of Nymphaea rubra Roxb. ex Andrews extract
page: 1143 - 1160
Author:Marisa Kamma, Wei Chao Lin, Shang-Chian Lau Sunee Chansakaow and Pimporn Leelapornpisid*
Vol.46 No.6 (November 2019) View: 922 Download:393
α-Galactosidase from Ling-Zhi Mushroom (Ganoderma lucidum)
page: 53 - 62
Author:Thida Sripuan* and Dararat Tongkao
Vol.31 No.1 (JANUARY 2004) View: 555 Download:147
Antibacterial, Antioxidant Properties and Bioactive Compounds of Thai Cultivated Mushroom Extracts Against Food-borne Bacterial Strains
page: 1713 - 1727
Author:Mathurot Chaiharn, Waya S. Phutdhawong, Doungporn Amornlerdpison and Weerachai Phutdhawong
Vol.45 No.4 (July 2018) View: 748 Download:414
Optimization of Succinic Acid Production by Actinobacillus sp. NP9-aA7 using Plackett-Burman Design Coupled with Box-Behnken Design
page: 1649 - 1666
Author:Sukanya Phuengjayaem,Somboon Tanasupawat and Siriluk Teeradakorn
Vol.45 No.4 (July 2018) View: 611 Download:439
Effect of Drying Process on the Physicochemical Properties and Biological Activities of Enzymatic Protein Hydrolysate from Shiitake Mushroom (Lentinula edodes)
page: 762 - 773
Author:Pasakawee Krittalak*, Banjongsinsiri Panida, Lekhavat Supaporn, Noojuy Nowwapan, Taksima Takunrat and Srimongkoluk Ubolwanna
Vol.45 No.2 (March 2018) View: 748 Download:849
Utilization of (Modified-) Ground Hazelnut Shells for Adsorption of Azo-metal Toxic Dyes: Empirical and ANFIS Modeling and Optimization
page: 342 - 354
Author:Musa Buyukada, Sibel Uzuner and Fatih Evrendilek
Vol.45 No.1 (January 2018) View: 623 Download:186
Content of Minerals and Trace Elements Determined by ICP-MS in Eleven Mushroom Species from Anatolia, Turkey
page: 939 - 945
Author:Gulsen Tel-Cayan*, Mehmet Ozturk, Mehmet E. Duru, Murat Yabanli and Aziz Turkoglu
Vol.44 No.3 (July 2017) View: 645 Download:195
Blazeispirol A, a Chemotaxonomic Marker from Mycelia of the Medicinal Mushroom Agaricus subrufescens
page: 298 - 308
Author:Naritsada Thongklang [a,b], Benjarong Thongbai [a,b], Sunita Chamyuang [b], Philippe Callac [c], Eka
Vol.44 No.2 (April 2017) View: 671 Download:217
Two species of Clitopilus (Entolomataceae, Agaricales) from Northern Thailand
page: 115 - 124
Author:Kritsana Jatuwong, Kevin D. Hyde, Samantha C. Karunarathna, Sunita Chamyoung and Pattana Kakumyan *
Vol.44 No.1 (JANUARY 2017) View: 616 Download:245
Effect of UV-B Irradiation on Contents of Ergosterol, Vitamin D2 and other Nutrients in Thai Edible Mushrooms
page: 45 - 53
Author:Nutsuda Banlangsawan and Niwat Sanoamuang
Vol.43 No.1 (JANUARY 2016) View: 614 Download:566
Efficient Synthesis of 4-Vinyl Guaiacol via Bioconversion of Ferulic Acid by Volvariella volvacea
page: 158 - 168
Author:Keerati Tanruean [a,b] and Nuansri Rakariyatham* [b,c]
Vol.43 No.1 (JANUARY 2016) View: 632 Download:180
Effects of Heat Treatment on Free Radical Scavenging Capacities and Phenolic Compounds in Tylopilus alboater Wild Edible Mushrooms
page: 1241 - 1249
Author:Nipaporn Sengkhamparn* and Nutchanat Phonkerd
Vol.41 No.5/2 (OCTOBER 2014) View: 626 Download:233
Proximate Analysis and Mineral Content of Laetiporus sulphureus Strain MFLUCC 12-0546 from Northern Thailand
page: 765 - 770
Author:Thatsanee Luangharn, Kevis D. Hyde and Ekachai Chukeatirote
Vol.41 No.4 (SPECIAL ISSUE 1) View: 620 Download:292
Discovering and domesticating wild tropical cultivatable mushrooms
page: 731 - 764
Author:Anan Thawthong, Samantha C. Kurunarathna, Naritsada Thongklang, Ekachai Chukeatirote, Pattana Kakumy
Vol.41 No.4 (SPECIAL ISSUE 1) View: 617 Download:202
Development of an Edible Wild Strain of Thai Oyster Mushroom for Economic Mushroom Production
page: 161 - 172
Author:Jaturong Kumla, Nakarin Suwannarach, Amornrat Jaiyasen, Boonsom Bussaban, and Saisamorn Lumyong*
Vol.40 No.2 (APRIL 2013) View: 569 Download:164
Optimization of Solid State Fermentation for Reducing Sugar Production from Agricultural Residues of Sweet Sorghum by Trichoderma harzianum
page: 270 - 280
Author:Anusith Thanapimmetha, Korsuk Vuttibunchon, Boosaree Titapiwatanakun and Penjit Srinophakun
Vol.39 No.2 (APRIL 2012) View: 521 Download:180
Optimization of Submerged Culture for the Production of Naphthoquinones Pigment by Fusarium verticillioides
page: 457 - 466
Author:Kongsak Boonyapranai, Rudeewan Tungpradit, Sorasak Lhieochaiphant and Suree Phutrakul
Vol.35 No.3 (SEPTEMBER 2008) View: 575 Download:152
Novel Elastic Nanovesicles for Cosmeceutical and Pharmaceutical Applications
page: 168 - 178
Author:Aranya Manosroi, Pensak Jantrawut, Narinthorn Khositsuntiwong, Worapaka Manosroi, and Jiradej Manosr
Vol.36 No.2 (MAY 2009) View: 581 Download:214
β -Glucosidase Production by Common Split Gill Mushroom (Schizophyllum commune Fr.) in Submerged Culture
page: 82 - 88
Author:Dararat Tongkao [a] and Thida Sripuan [b]
Vol.27 No.2 (DECEMBER 2000) View: 3,474 Download:290
Antioxidant and Anti-inflammatory Activities of Brown Marine Alga, Padina minor Yamada
page: 507 - 516
Author:Yuwadee Peerapornpisal, Doungporn Amornlerdpison, Utan Jamjai, Tawat Taesotikul, Yanee Pongpaibul,
Vol.37 No.3 (SEPTEMBER 2010) View: 625 Download:264



Search in this journal


Document Search


Author Search

A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z

Popular Search






Chiang Mai Journal of Science

Faculty of Science, Chiang Mai University
239 Huaykaew Road, Tumbol Suthep, Amphur Muang, Chiang Mai 50200 THAILAND
Tel: +6653-943-467




Faculty of Science,
Chiang Mai University




EMAIL
cmjs@cmu.ac.th




Copyrights © Since 2021 All Rights Reserved by Chiang Mai Journal of Science