Chiang Mai Journal of Science

     This work aims to synthesize Zn-Ag doped hydroxyapatite using glutinous rice (GRHA) as a template through ultrasonic irradiation coupled with sol-gel technique. The prepared materials are referred to as Ca_9.0Zn_1.0-xAg_x(PO₄)₆(OH)₂) which consist of Zn2+ and Ag⁺ varying molar ratios (x= 0.0, 0.25, 0.50, 0.75 and 1.0). The synthesized samples were characterized by various techniques. XRD results revealed that Zn²⁺ and Ag⁺ were incorporated into a hexagonal framework of HA. FT-IR analysis showed that the main functional groups were hydroxyl and phosphate groups. SEM images showed a rough surface morphology, which consists of very small spherical particles. TEM images revealed the homogeneous distribution of Zn²⁺ and Ag⁺ in the synthesized samples. Antibacterial activity of the Zn-Ag doped GRHA against five strains of bacteria including S. aureus, B. cereus, B. subtilis, P. aeruginosa and E. coli. Zn_0.75Ag_0.25 doped GRHA showed excellent antibacterial activity against all strains except P. aeruginosa.