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Increased Antibacterial Activity of Zinc-Silver Doped Hydroxyapatite Synthesized via Ultrasonic in Combination with Sol-Gel Technique using Glutinous Rice as a Template


Paper Type 
 Contributed Paper
Title 
 Increased Antibacterial Activity of Zinc-Silver Doped Hydroxyapatite Synthesized via Ultrasonic in Combination with Sol-Gel Technique using Glutinous Rice as a Template
Author 
 Piaw Phatai, Sirilak Kamonwannasit, Sakuntala Siri-udom, Cybelle Morales Futalan, Pongtanawat Khemthong, Saran Youngjan, Teera Butburee, Khongvit Prasitnok and Orrasa Prasitnok
Email 
 orrasa.p@msu.ac.th
Abstract:

     This work aims to synthesize Zn-Ag doped hydroxyapatite using glutinous rice (GRHA) as a template through ultrasonic irradiation coupled with sol-gel technique. The prepared materials are referred to as Ca9.0Zn1.0-xAgx(PO4)6(OH)2) which consist of Zn2+ and Ag+ varying molar ratios (x= 0.0, 0.25, 0.50, 0.75 and 1.0). The synthesized samples were characterized by various techniques. XRD results revealed that Zn2+ and Ag+ were incorporated into a hexagonal framework of HA. FT-IR analysis showed that the main functional groups were hydroxyl and phosphate groups. SEM images showed a rough surface morphology, which consists of very small spherical particles. TEM images revealed the homogeneous distribution of Zn2+ and Ag+ in the synthesized samples. Antibacterial activity of the Zn-Ag doped GRHA against five strains of bacteria including S. aureus, B. cereus, B. subtilis, P. aeruginosa and E. coli. Zn0.75Ag0.25 doped GRHA showed excellent antibacterial activity against all strains except P. aeruginosa.
Article ID
 e2024044
Received Date 
 2024-01-24
Revised Date 
 2024-04-08
Accepted Date 
 2024-04-17
Full Text 
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Keyword 
 antibacterial activity, glutinous rice, sol-gel technique, ultrasonic, zinc-silver doped hydroxyapatite
Volume 
 Vol.51 No.3 (May 2024)
DOI 
 https://doi.org/10.12982/CMJS.2024.044
Citation 
 Phatai P.,Kamonwannasit S.,Siri-udom S.,Futalan C.,M.,Khemthong P.,Youngjan S., et al., Increased Antibacterial Activity of Zinc-Silver Doped Hydroxyapatite Synthesized via Ultrasonic in Combination with Sol-Gel Technique using Glutinous Rice as a Template, Chiang Mai Journal of Science, 2024; 51(3): e2024044. DOI 10.12982/CMJS.2024.044.
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