Submit your paper 
Download Template JOURNAL DETAIL
Bacterial Cellulose and Bacterial Cellulose/Chitosan Films Containing Mangosteen Pericarp Extract for Wound Dressings
Paper Type  |
Contributed Paper |
Title |
Bacterial Cellulose and Bacterial Cellulose/Chitosan Films Containing Mangosteen Pericarp Extract for Wound Dressings |
Author |
Pronpatsorn Moonsungnoen, Duangjai Ochaikul and Pathavuth Monvisade |
Email |
daungjai.oc@kmitl.ac.th |
|
Abstract: Appropriate wound dressings for maintaining a moist wound environment, inducing re-epithelialization and protection from infection have been widely developed. Recently, many biocompatible polymers and bioactive substances have been extensively used for wound healing applications. In this study, bacterial cellulose film (BC-MPE film) and bacterial cellulose/chitosan film (BC/CH-MPE film) containing 1.56 mg/mL of mangosteen pericarp extract (MPE) were prepared. Antibacterial activity, cytotoxicity, physical and mechanical properties of the dry films were investigated. The BC film with MPE presented non-cytotoxic effect after 20 h of exposure to mouse fibroblast cell line (L929). The prepared films performed carrier of bioactive compounds that exhibited antibacterial activity against bacterial infection in burn wounds. The morphology of the films showed the characteristic of ultra-fine network structures with the entrapment of compounds. In addition, the compact structure was observed due to the rapid moisture loss during vacuum drying process. SEM images also showed that BC/CH-MPE film formed layers with chitosan entrapment causing the film to become thicker than BC-MPE film. The formation of MPE and chitosan in modified films was also confirmed by FTIR. The compact structure of BC/CH-MPE film led to the decrease in cumulative release of xanthone, WVTR and WAC. Moreover, the existence of chitosan in BC layers provided more flexible properties than the non-chitosan film. The chitosan addition demonstrated an influence of barrier film to protect the wound. Therefore, BC and chitosan were considered as suitable candidates for wound dressing material and xanthone content of MPE promoted wound healing as an effective therapeutic agent. |
|
Start & End Page |
952 - 968 |
Received Date |
2020-10-19 |
Revised Date |
2021-01-11 |
Accepted Date |
2021-01-14 |
Full Text |
Download |
Keyword |
bacterial cellulose, chitosan, mangosteen pericarp, wound dressings |
Volume |
Vol.48 No.4 (July 2021) |
DOI |
|
Citation |
Moonsungnoen P., Ochaikul D. and Monvisade P., Bacterial Cellulose and Bacterial Cellulose/Chitosan Films Containing Mangosteen Pericarp Extract for Wound Dressings, Chiang Mai Journal of Science, 2021; 48(4): 952-968. |
SDGs |
|
| View:1,450 Download:605 | |
RELATED ARTICLE
Article ID: e2025008
Author:Melody Kimi and Chee Jiun Chong
Vol.52 No.1 (January 2025) View: 246 Download:107
Article ID: e2025007
Author:Min-Chi Chong and Jui-Yu Chou
Vol.52 No.1 (January 2025) View: 243 Download:98
Article ID: e2023033
Author:Sonthirat Charoenrak, Mamoru Wakayama, Suporn Charumanee, Panee Sirisa-ard, Sittisin Bovonsombut, Suwalee Kiatkarun, Thararat Chitov and Sakunnee Bovonsombut
Vol.50 No.3 (May 2023) View: 726 Download:504
page: 1135 - 1149
Author:Nattapong Pinpru, Thitirat Charoonsuk, Thanong Phanasun, Machima Soponpong, Theerachai Bongkarn, Somsak Woramongkolchai and Naratip Vittayakorn
Vol.49 No.4 (July 2022) View: 1,615 Download:338
page: 123 - 131
Author:Surin Saipanya*, Ruangsri Watanesk, Wimol Saiyasombat and Sunanta Wangkarn
Vol.30 No.2 (AUGUST 2003) View: 660 Download:257
page: 2374 - 2380
Author:Lerdluck Kaewvimol
Vol.45 No.6 (September 2018) View: 780 Download:266
page: 961 - 972
Author:Tu Phuong Pham Le and Wanwipa Siriwatwechakul*
Vol.45 No.2 (March 2018) View: 700 Download:301
page: 1611 - 1623
Author:Safiah Saah, Kwunchit Oungbho* and Soottawat Benjakul
Vol.44 No.4 (October 2017) View: 786 Download:305
page: 1149 - 1158
Author:Supreedee Sungkharak [a, b], Nicha Supasit [b], Sasiluk Choopan [b] and Suwipa Ungphaiboon*[a, b]
Vol.43 No.5 (OCTOBER 2016) View: 726 Download:527
page: 1070 - 1076
Author:Jiraporn Palee [a], Srisulak Dheeranupattana* [b], Sunanta Wangkarn [c], Stephen G. Pyne [d] and Alison T. Ung [e]
Vol.43 No.5 (OCTOBER 2016) View: 644 Download:273
page: 946 - 958
Author:Thida Kaewkod [a], Khajornsak Tragoolpua [b] and Yingmanee Tragoolpua* [a]
Vol.43 No.5 (OCTOBER 2016) View: 681 Download:318
page: 918 - 929
Author:Tanyarat Poothawan and Khomsorn Lomthaisong
Vol.42 No.4 (OCTOBER 2015) View: 667 Download:215
page: 393 - 400
Author:Thammasit Vongsetskul, Kewalin Phaenthong, Ratana Chanthateyanonth, Panya Sunintaboon and Pramuan T
Vol.42 No.2 (APRIL 2015) View: 10,760 Download:321
page: 44 - 51
Author:Surawut Sangmanee, Santhana Nakapong, Kamontip Kuttiyawong and Rath Pichyangkura
Vol.42 No.1 (JANUARY 2015) View: 687 Download:211
page: 133 - 137
Author:Pornchai Rachtanapun and Panchat Wongchaiya
Vol.39 No.1 (JANUARY 2012) View: 700 Download:143
page: 95 - 104
Author:Piyaporn Kampeerapappun, Trongsu Phattararittigul, Sutida Jittrong and Dararat Kullachod
Vol.38 No.1 (JANUARY 2011) View: 713 Download:219
page: 183 - 189
Author:Kanarat Nalampang, Nantarat Suebsanit, Chinanat Witthayaprapakorn, and Robert Molloy
Vol.34 No.2 (MAY 2007) View: 717 Download:233
page: 95 - 102
Author:Boonyarit Nuntakumjorn, Wuthichok Khumsalud, Naret Vetsavas, Thoranin Sujjaviriyasup and Chantarapor
Vol.35 No.1 (JANUARY 2008) View: 665 Download:274
page: 501 - 505
Author:Phuriwat L eesawat *[a], K arn V earnsilp[a], Nijaporn Y anasarn [a] and Peeracha Thanawatta
Vol.32 No.3 (SEPTEMBER 2005) View: 648 Download:274
Copyrights © Since 2021 All Rights Reserved by Chiang Mai Journal of Science