Chiang Mai Journal of Science

 The consumption of red dragon fruit in various forms is claimed to provide lipid lowering effect. However, the health benefit of fermented dragon fruit product was not well studied. Therefore, this research was designed to investigate the effect of fermented dragon fruit (Hylocereus polyrhizus) liquid on the lipid profile in Golden Syrian hamster. Hamsters were fed with 1 mL of two different samples, being the fermented fruit liquid (SA) and the pasteurized fermented fruit liquid (SB) for eight consecutive weeks. Another group of hamsters were treated with a high cholesterol diet for the same time duration to serve as a positive control. Current results indicated that both hamsters fed with SA (HCA) and SB (HCB) did not show any remarkable change on the weight of organs (liver, kidney, heart) and fecal excreted. However, SA and SB were found to reduce the triglycerides level, in particular, SA significantly (p<0.05) reduced the triglycerides level in hamsters up to 46.2%, in comparison to that of the positive control (HC) on the 16^th week. Therefore, it could be deduced that the consumption of fermented dragon fruit (Hylocereus polyrhizus) may have the potential to suppress the serum triglyceride level in hamsters. However, further study need to be conducted.