Submit your paper 
Download Template JOURNAL DETAIL
Characterization and Expression Analysis of the STAT Pathway in Anopheles dirus
Paper Type  |
Contributed Paper |
Title |
Characterization and Expression Analysis of the STAT Pathway in Anopheles dirus |
Author |
Jonathan Wee Kent Liew, Cherng Shii Leong, Meng Li Wong, Indra Vythilingam, Mun Yik Fong and Yee Ling Lau |
Email |
lauyeeling@um.edu.my |
|
Abstract: The Janus kinase-signal transducers and activators of transcription (JAK-STAT) pathway is one of the main signaling pathways mediating immune responses towards malaria parasites in Anopheles. Core components of the STAT pathway are STAT, suppressor of cytokine signaling (SOCS) protein, and protein inhibitor of activated STAT (PIAS) protein. However, this pathway is the least studied among the three major signaling pathways. Recent study found that Anopheles dirus lacks a second intronless STAT. The implication of this phenomenon is still unclear. Moreover, molecular understanding of An. dirus is scarce. Thus, the three components of the pathway were studied using an Anopheles dirus/Plasmodium berghei experimental model. The three proteins were sequenced and characterized. The STAT, PIAS and SOCS proteins exhibited high sequence similarity with those of other Anopheles. Nonetheless, there were no significant changes in the expression levels of the genes post Plasmodium berghei infection. The current study warrants further investigation on the JAK-STAT pathway in Anopheles. More investigations on the Anopheles spp. in different geographical regionsshould be pursued, to understand the possible differences in the JAK-STAT pathway among these Anopheles. |
|
Start & End Page |
1728 - 1744 |
Received Date |
2017-05-11 |
Revised Date |
|
Accepted Date |
2017-07-04 |
Full Text |
Download |
Keyword |
Anopheles dirus, Plasmodium berghei, STAT, PIAS, SOCS, experimental model |
Volume |
Vol.45 No.4 (July 2018) |
DOI |
|
Citation |
Liew J.W.K., Leong C.S., Wong M.L., Vythilingam I., Fong M.Y. and Lau Y.L., Characterization and Expression Analysis of the STAT Pathway in Anopheles dirus, Chiang Mai Journal of Science, 2018; 45(4): 1728-1744. |
SDGs |
|
| View:700 Download:267 | |
RELATED ARTICLE
Soc Estimation of Li-ion Battery Based on Adaptive CKF Algorithm
Article ID: e2023063
Author:Zhengjun Huang, Yu Chen and Meifang Zhou
Vol.50 No.6 (November 2023) View: 539 Download:348
Article ID: e2023063
Author:Zhengjun Huang, Yu Chen and Meifang Zhou
Vol.50 No.6 (November 2023) View: 539 Download:348
Purification of TiO2 from Leucoxene for the Synthesis of NIR-Reflective Cr-doped CaTiO3 Pigment
page: 93 - 104
Author:Kanyawee Sinmongkolkul, Pattana Rakkwamsuk, Tippaban Palathai, Sasijuta Wattanarach, Parjaree Thavorniti and Sitthisuntorn Supothina
Vol.49 No.1 (Special Issue I : Jan 2022) View: 1,489 Download:642
page: 93 - 104
Author:Kanyawee Sinmongkolkul, Pattana Rakkwamsuk, Tippaban Palathai, Sasijuta Wattanarach, Parjaree Thavorniti and Sitthisuntorn Supothina
Vol.49 No.1 (Special Issue I : Jan 2022) View: 1,489 Download:642
Real-Time Analysis of Ozone Concentration Using Nonparametric Model of High-Dimensional Data
page: 1173 - 1185
Author:Ibrahim M. Almanjahie, Zoulikha Kaid, Zouaoui Chikr Elmezouar and Ali Laksaci
Vol.48 No.4 (July 2021) View: 725 Download:208
page: 1173 - 1185
Author:Ibrahim M. Almanjahie, Zoulikha Kaid, Zouaoui Chikr Elmezouar and Ali Laksaci
Vol.48 No.4 (July 2021) View: 725 Download:208
A Compact, Portable, and Low-cost Potentiostat with Smartphone for Electrochemical Sensors
page: 1183 - 1194
Author:Watcharin Permwong, Chidkamon Thunkhamrak, Jantima Upan, Jaroon Jakmunee and Somkid Pencharee
Vol.47 No.6 (November 2020) View: 806 Download:732
page: 1183 - 1194
Author:Watcharin Permwong, Chidkamon Thunkhamrak, Jantima Upan, Jaroon Jakmunee and Somkid Pencharee
Vol.47 No.6 (November 2020) View: 806 Download:732
SDGs:
Iron(II) Complexes Containing 1,2,4-Triazole-Pyridine and the Substituted Derivatives; Electronic Properties and Magnetic Moments
page: 1068 - 1080
Author:Kristian Handoyo Sugiyarto, Cornelia Budimarwanti and Harold Andrew Goodwin
Vol.47 No.5 (September 2020) View: 830 Download:488
page: 1068 - 1080
Author:Kristian Handoyo Sugiyarto, Cornelia Budimarwanti and Harold Andrew Goodwin
Vol.47 No.5 (September 2020) View: 830 Download:488
Synthesis and Optical Band Gap Study of NIR-Reflective CoFe2O4 Black Pigments Doped with MgO, CaO and Al2O3
page: 686 - 699
Author:Nuchjarin Sangwong, Mantana Suwan and Sitthisuntorn Supothina*
Vol.47 No.4 (Special Issue II : July 2020) View: 798 Download:1,413
page: 686 - 699
Author:Nuchjarin Sangwong, Mantana Suwan and Sitthisuntorn Supothina*
Vol.47 No.4 (Special Issue II : July 2020) View: 798 Download:1,413
Effects of Fe Substitution on the Structural and Magnetic Properties of CuBO2 Delafossite Oxide
page: 665 - 672
Author:Sornamol Traiphop and Teerasak Kamwanna*
Vol.47 No.4 (Special Issue II : July 2020) View: 1,155 Download:1,098
page: 665 - 672
Author:Sornamol Traiphop and Teerasak Kamwanna*
Vol.47 No.4 (Special Issue II : July 2020) View: 1,155 Download:1,098
Effect of Calcination Condition on Phase Formation Characteristics of NdBa2Cu3Oy Powder Prepared by Solidstate Reaction
page: 654 - 664
Author:Paitoon Boonsong, Pimpilai Wannasut and Anucha Watcharapasorn*
Vol.47 No.4 (Special Issue II : July 2020) View: 830 Download:1,097
page: 654 - 664
Author:Paitoon Boonsong, Pimpilai Wannasut and Anucha Watcharapasorn*
Vol.47 No.4 (Special Issue II : July 2020) View: 830 Download:1,097
SDGs:
Catalytic Activity of Bimetallic Au@Pt Core-Shell Over CeO2-Al2O3 for CO Oxidation Reaction
page: 278 - 287
Author:Wichet Lamai and Akkarat Wongkaew*
Vol.47 No.2 (Special Issue I : March 2020) View: 1,559 Download:690
page: 278 - 287
Author:Wichet Lamai and Akkarat Wongkaew*
Vol.47 No.2 (Special Issue I : March 2020) View: 1,559 Download:690
Electronic Properties of Iron(II) Complexes of 2-(Pyridin-2-yl)benzoxazole
page: 756 - 765
Author:Kristian Handoyo Sugiyarto* and Harold Andrew Goodwin
Vol.46 No.4 (July 2019) View: 661 Download:302
page: 756 - 765
Author:Kristian Handoyo Sugiyarto* and Harold Andrew Goodwin
Vol.46 No.4 (July 2019) View: 661 Download:302
Purification and Characterization of an Extracellular Chitinase from Bacillus thuringiensis R 176 using Solid State Fermentation with Shrimp Shells Waste
page: 495 - 509
Author:Mathurot Chaiharn, Abhinya Pikomol and Saisamorn Lumyoung
Vol.46 No.3 (May 2019) View: 695 Download:300
page: 495 - 509
Author:Mathurot Chaiharn, Abhinya Pikomol and Saisamorn Lumyoung
Vol.46 No.3 (May 2019) View: 695 Download:300
Comparison Among Alpha-tricalcium Phosphate Synthesized by Solid State Reaction and Wet Chemical Reaction for Calcium Phosphate Cements
page: 2123 - 2131
Author:Paritat Thaitalay, Nuan La-ong Srakaew and Sirirat Tubsungnoen Rattanachan
Vol.45 No.5 (Special 2018) View: 853 Download:308
page: 2123 - 2131
Author:Paritat Thaitalay, Nuan La-ong Srakaew and Sirirat Tubsungnoen Rattanachan
Vol.45 No.5 (Special 2018) View: 853 Download:308
In Vitro Cultivation of Porcine Chondrocytes on Fully Surface-Modified Polycaprolactone Scaffold:
Static versus Dynamic Cultures
page: 2092 - 2104
Author:Pakkanun Kaewkong, Paweena Uppanan, Wasana Kosorn, Marut Wongcumchang, Pronrumpa Kanjanasingh, Tareerat Lertwimol and Wanida Janvikul
Vol.45 No.5 (Special 2018) View: 732 Download:257
page: 2092 - 2104
Author:Pakkanun Kaewkong, Paweena Uppanan, Wasana Kosorn, Marut Wongcumchang, Pronrumpa Kanjanasingh, Tareerat Lertwimol and Wanida Janvikul
Vol.45 No.5 (Special 2018) View: 732 Download:257
Iron Reduces Iron: A Spectroelectrochemical Insight of Ligand Effect on Iron Redox Potential
page: 1087 - 1098
Author:Shabnum Bashir, Mohammad Mustafa, Syed Wasim Safvi, Nisar Ahmad Farhad and Masood Ahmad Rizvi*
Vol.45 No.2 (March 2018) View: 666 Download:452
page: 1087 - 1098
Author:Shabnum Bashir, Mohammad Mustafa, Syed Wasim Safvi, Nisar Ahmad Farhad and Masood Ahmad Rizvi*
Vol.45 No.2 (March 2018) View: 666 Download:452
Design and Development of User-friendly Computing Tool for Path Coefficient Analysis with Application to Mung Bean (Vigna Radiate L. Wilczek) Traits Towards Seed Yield
page: 634 - 644
Author:Muhammad Amin, Lixin Song, Ruchdee Binmad, Jafar Hussain and Hidayat Ullah
Vol.45 No.1 (January 2018) View: 653 Download:195
page: 634 - 644
Author:Muhammad Amin, Lixin Song, Ruchdee Binmad, Jafar Hussain and Hidayat Ullah
Vol.45 No.1 (January 2018) View: 653 Download:195
Detection of Bacterial Communities in
Volatile-organic-compound (VOC)-contaminated Soil in an Industrial Estate in Eastern Thailand by
PCR-DGGE Analysis
page: 742 - 750
Author:Manatsawat Sriwichai, Fairda Malem, Mujalin K. Pholchan and Sakunnee Bovonsombut*
Vol.44 No.3 (July 2017) View: 755 Download:254
page: 742 - 750
Author:Manatsawat Sriwichai, Fairda Malem, Mujalin K. Pholchan and Sakunnee Bovonsombut*
Vol.44 No.3 (July 2017) View: 755 Download:254
On a Mechanical Interpretation of Self-energy in Electrostatics and Magnetostatics and an Interpretation of Faraday's Law
page: 248 - 254
Author:Chankit Khanchong
Vol.44 No.1 (JANUARY 2017) View: 647 Download:334
page: 248 - 254
Author:Chankit Khanchong
Vol.44 No.1 (JANUARY 2017) View: 647 Download:334
Antibacterial Activity Against Acne Involved Bacteria of Chitosan in a Soluble State and as Nanoparticles
page: 1149 - 1158
Author:Supreedee Sungkharak [a, b], Nicha Supasit [b], Sasiluk Choopan [b] and Suwipa Ungphaiboon*[a, b]
Vol.43 No.5 (OCTOBER 2016) View: 772 Download:537
page: 1149 - 1158
Author:Supreedee Sungkharak [a, b], Nicha Supasit [b], Sasiluk Choopan [b] and Suwipa Ungphaiboon*[a, b]
Vol.43 No.5 (OCTOBER 2016) View: 772 Download:537
Dye-sensitized Solar Cell Based on Composite Poly(ethylene oxide) Electrolyte with Natural Carmine Pigment
page: 1113 - 1121
Author:Surassawatee Jamikorn [a], Suthida Vivekaphirat [a], Voranuch Somsongkul [c], Weera Suanthaisong [a], Atittaya Naikaew [b], Atchana Wongchaisuwat [a] and Marisa Arunchaiya*[b]
Vol.43 No.5 (OCTOBER 2016) View: 629 Download:211
page: 1113 - 1121
Author:Surassawatee Jamikorn [a], Suthida Vivekaphirat [a], Voranuch Somsongkul [c], Weera Suanthaisong [a], Atittaya Naikaew [b], Atchana Wongchaisuwat [a] and Marisa Arunchaiya*[b]
Vol.43 No.5 (OCTOBER 2016) View: 629 Download:211
Enhanced Production of Cordycepin by Solid State Fermentation of Cordyceps militaris using Additives
page: 972 - 984
Author:Ting-Chi Wen [a]+, Chao Kang [b]+, Ze-Bing Meng [a], Yong-Bin Qi [a], Kevin D. Hyde [c, d] and Ji-Chuan Kang* [a]
Vol.43 No.5 (OCTOBER 2016) View: 932 Download:238
page: 972 - 984
Author:Ting-Chi Wen [a]+, Chao Kang [b]+, Ze-Bing Meng [a], Yong-Bin Qi [a], Kevin D. Hyde [c, d] and Ji-Chuan Kang* [a]
Vol.43 No.5 (OCTOBER 2016) View: 932 Download:238
Three Non-parametric Control Charts Based on Ranked Set Sampling
page: 915 - 930
Author:Waliporn Tapang, Adisak Pongpullponsak* and Sukuman Sarikavanij
Vol.43 No.4 (JULY 2016) View: 653 Download:348
page: 915 - 930
Author:Waliporn Tapang, Adisak Pongpullponsak* and Sukuman Sarikavanij
Vol.43 No.4 (JULY 2016) View: 653 Download:348
Helvolic Acid, A Secondary Metabolite Produced by Neosartorya spinosa KKU-1NK1 and Its Biological Activities
page: 484 - 494
Author:Wareerat Sanmanoch [a], Wiyada Mongkolthanaruk [a], Somdej Kanokmedhakul [b], Tadanori Aimi [c] and Sophon Boonlue *[a, b]
Vol.43 No.3 (APRIL 2016) View: 707 Download:288
page: 484 - 494
Author:Wareerat Sanmanoch [a], Wiyada Mongkolthanaruk [a], Somdej Kanokmedhakul [b], Tadanori Aimi [c] and Sophon Boonlue *[a, b]
Vol.43 No.3 (APRIL 2016) View: 707 Download:288
Semi-Solid State Joining of SSM Aluminum Alloys Using Brazing ZA27
page: 393 - 401
Author:Thammanoon Phonin[a] , Prapas Muangjunburee*[b]
Vol.43 No.2 (SPECIAL ISSUE 1) View: 648 Download:221
page: 393 - 401
Author:Thammanoon Phonin[a] , Prapas Muangjunburee*[b]
Vol.43 No.2 (SPECIAL ISSUE 1) View: 648 Download:221
Utilization of agro-industrial products for increasing red pigment production of Monascus purpureus AHK12
page: 331 - 338
Author:Pongrawee Nimnoi , Neelawan Pongsilp, Saisamorn Lumyong
Vol.42 No.2 (APRIL 2015) View: 704 Download:213
page: 331 - 338
Author:Pongrawee Nimnoi , Neelawan Pongsilp, Saisamorn Lumyong
Vol.42 No.2 (APRIL 2015) View: 704 Download:213
Spectroscopic electron temperature measurement in methane/helium plasma during diamond-like carbon coating
page: 248 - 257
Author:Artit Chingsungnoen , Vittaya Amornkitbamrung
Vol.42 No.1 (JANUARY 2015) View: 1,145 Download:225
page: 248 - 257
Author:Artit Chingsungnoen , Vittaya Amornkitbamrung
Vol.42 No.1 (JANUARY 2015) View: 1,145 Download:225
Exact Solution for Average Run Length of CUSUM Charts for MA(1) Process
page: 1449 - 1456
Author:Kanita Petcharat[a], Yupaporn Areepong*[a], Saowanit Sukparungsee[a] and Gabriel Mititelu[b]
Vol.41 No.5/2 (OCTOBER 2014) View: 952 Download:236
page: 1449 - 1456
Author:Kanita Petcharat[a], Yupaporn Areepong*[a], Saowanit Sukparungsee[a] and Gabriel Mititelu[b]
Vol.41 No.5/2 (OCTOBER 2014) View: 952 Download:236
Effect of Morinda citrifolia Linn. leaf extracts on in vitro lipase activity
page: 1182 - 1193
Author:Aurasorn Saraphanchotiwitthaya*[a], Pattana Sripalakit [b]
Vol.41 No.5/1 (OCTOBER 2014) View: 1,106 Download:261
page: 1182 - 1193
Author:Aurasorn Saraphanchotiwitthaya*[a], Pattana Sripalakit [b]
Vol.41 No.5/1 (OCTOBER 2014) View: 1,106 Download:261
Optimization of Solid-state Fermentation for Fruiting Body Growth and Cordecepin Production by Cordyceps militaris
page: 858 - 872
Author:Ting-chi Wen, Cuang-rong Li, Ji-chuan Kang*,Chao Kang and Kevin D. Hyde
Vol.41 No.4 (SPECIAL ISSUE 1) View: 838 Download:537
page: 858 - 872
Author:Ting-chi Wen, Cuang-rong Li, Ji-chuan Kang*,Chao Kang and Kevin D. Hyde
Vol.41 No.4 (SPECIAL ISSUE 1) View: 838 Download:537
Phenotypic Marking of Cordyceps militaris Fruiting-Bodies and Their Cordycepin Production
page: 846 - 857
Author:Ting-chi Wen, Ji-chuan Kang*, Kevin D. Hyde, Guang-rong Li, Chao Kang and Xu Chen
Vol.41 No.4 (SPECIAL ISSUE 1) View: 774 Download:276
page: 846 - 857
Author:Ting-chi Wen, Ji-chuan Kang*, Kevin D. Hyde, Guang-rong Li, Chao Kang and Xu Chen
Vol.41 No.4 (SPECIAL ISSUE 1) View: 774 Download:276
Modeling Incidence Rates of Terrorism Injuries in Southern Thailand
page: 743 - 749
Author:Sumpunt Khongmark*[a] and Metta Kuning [b]
Vol.40 No.4 (OCTOBER 2013) View: 614 Download:226
page: 743 - 749
Author:Sumpunt Khongmark*[a] and Metta Kuning [b]
Vol.40 No.4 (OCTOBER 2013) View: 614 Download:226
Theoretical Investigation of Superconducting State Parameters of (Ni33Zr67)1-xCox Bulk Metallic Glasses
page: 507 - 516
Author:Aditya M. Vora*
Vol.40 No.3 (JULY 2013) View: 621 Download:350
page: 507 - 516
Author:Aditya M. Vora*
Vol.40 No.3 (JULY 2013) View: 621 Download:350
Optimal Rain Gauge Network Design and Spatial Precipitation Mapping based on Geostatistical Analysis from Co-located Elevation and Humidity Data
page: 187 - 197
Author:Aksara Putthividhya *[a] and Kenji Tanaka [b]
Vol.40 No.2 (APRIL 2013) View: 647 Download:247
page: 187 - 197
Author:Aksara Putthividhya *[a] and Kenji Tanaka [b]
Vol.40 No.2 (APRIL 2013) View: 647 Download:247
Analysis of Average Run Length for CUSUM Procedure with Negative Exponential Data
page: 200 - 208
Author:Jaruchat Busaba, Saowanit Sukparungsee, Yapaporn Areepong and Gabriel Mititelu
Vol.39 No.2 (APRIL 2012) View: 677 Download:180
page: 200 - 208
Author:Jaruchat Busaba, Saowanit Sukparungsee, Yapaporn Areepong and Gabriel Mititelu
Vol.39 No.2 (APRIL 2012) View: 677 Download:180
Water Quality and Trophic Status in Main Rivers of
Thailand
page: 280 - 294
Author:Pongpan Leelahakriengkrai*[a] and Yuwadee Peerapornpisal [a,b]
Vol.38 No.2 (APRIL 2011) View: 673 Download:422
page: 280 - 294
Author:Pongpan Leelahakriengkrai*[a] and Yuwadee Peerapornpisal [a,b]
Vol.38 No.2 (APRIL 2011) View: 673 Download:422
Self-Diffusion Coefficient of Liquid Alkali Metals
page: 125 - 129
Author:Sant K. Srivastava* [a] and Kishor G. Kolhe [b]
Vol.31 No.2 May 2004 View: 706 Download:168
page: 125 - 129
Author:Sant K. Srivastava* [a] and Kishor G. Kolhe [b]
Vol.31 No.2 May 2004 View: 706 Download:168
Nonlinear Model-Based Control for Parabolic Partial
Differential Equations Systems
page: 221 - 228
Author:Atthasit Tawai and Chanin Panjapornpon
Vol.35 No.1 (JANUARY 2008) View: 631 Download:829
page: 221 - 228
Author:Atthasit Tawai and Chanin Panjapornpon
Vol.35 No.1 (JANUARY 2008) View: 631 Download:829
Estimation of Water Content in PEM Fuel Cell
page: 212 - 220
Author:Chinnavat Thawornkuno and Chanin Panjapornpon
Vol.35 No.1 (JANUARY 2008) View: 666 Download:914
page: 212 - 220
Author:Chinnavat Thawornkuno and Chanin Panjapornpon
Vol.35 No.1 (JANUARY 2008) View: 666 Download:914
Hydrodynamics of Mixture Between PVC Resin and
Anti-static Powder in Circulating Fluidized Bed
page: 29 - 34
Author:Thiti Saichua and Suchaya Nitivattananon
Vol.35 No.1 (JANUARY 2008) View: 658 Download:291
page: 29 - 34
Author:Thiti Saichua and Suchaya Nitivattananon
Vol.35 No.1 (JANUARY 2008) View: 658 Download:291
The Response of Aluminium Foams Under
Quasi-Static Loading
page: 241 - 249
Author:Mohamad R. Said and Chee-Fai Tan
Vol.35 No.2 (MAY 2008) View: 722 Download:214
page: 241 - 249
Author:Mohamad R. Said and Chee-Fai Tan
Vol.35 No.2 (MAY 2008) View: 722 Download:214
Microstructural Restoration by HIP and Heat Treatment
Processes in Cast Nickel Based Superalloy, IN-738
page: 287 - 295
Author:Panyawat Wangyao, Gobboon Lothongkum, Viyaporn Krongtong, Weerasak Homkrajai and Nutthita Chuankrerk
Vol.36 No.3 (SEPTEMBER 2009) View: 778 Download:234
page: 287 - 295
Author:Panyawat Wangyao, Gobboon Lothongkum, Viyaporn Krongtong, Weerasak Homkrajai and Nutthita Chuankrerk
Vol.36 No.3 (SEPTEMBER 2009) View: 778 Download:234
Copyrights © Since 2021 All Rights Reserved by Chiang Mai Journal of Science