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One-pot Green Procedure for the Mannich Reaction Catalyzed by a Task-specific Ionic Liquid


Paper Type 
Contributed Paper
Title 
One-pot Green Procedure for the Mannich Reaction Catalyzed by a Task-specific Ionic Liquid
Author 
Guozheng Zhao and Ming Lu
Email 
lumingchem@163.com
Abstract:

A  three-component  Mannich-type  reaction  of  aromatic  aldehydes, aromatic  amines, and ketones  was  catalyzed  by  a  novel  task-specific  ionic  liquid, 4-(3-sulfopropyl) morpholinium  hydrogen  sulfate ([C3SO3Hnhm]HSO4)  at  room  temperature  to  give  various  β-amino  carbonyl  compounds  in  good  yields. The  products  could  simply  be  separated  from  catalyst/ethanol, and the  catalytic  system  could  be  recycled  and reused  for  six  times  without  noticeably  decreasing  catalytic  activity.

 

Start & End Page 
49 - 58
Received Date 
2011-06-14
Revised Date 
Accepted Date 
2011-10-15
Full Text 
  Download
Keyword 
Mannich reaction, task-specific ionic liquid, catalyst
Volume 
Vol.39 No.1 (JANUARY 2012)
DOI 
Citation 
Zhao G. and Lu M., One-pot Green Procedure for the Mannich Reaction Catalyzed by a Task-specific Ionic Liquid, Chiang Mai J. Sci., 2012; 39(1): 49-58.
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