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Green Synthesis of Bis(indolyl)methanes Catalysed by Salicylic Acid
Paper Type  |
Contributed Paper |
Title |
Green Synthesis of Bis(indolyl)methanes Catalysed by Salicylic Acid |
Author |
Hoda Banari, Hamzeh Kiyani and Alireza Pourali |
Email |
hkiyani@du.ac.ir |
|
Abstract: In this contribution, salicylic acid (SA) has been used to catalyze synthesis of a series of biologically relevant 3,3¢-bis(indolyl)methanes (BIMs) via the electrophilic substitution of indole derivatives on aldehyde compounds. The optimum catalyst loading was observed at 15 mol%. The procedure is simple and the expected bis-heterocyclic compounds were isolated in good to high yields. The present protocol provides the advantages of convenience, mild reaction conditions, eco-friendliness, energy-saving, and no use of hazardous solvents. |
|
Start & End Page |
413 - 420 |
Received Date |
2016-03-01 |
Revised Date |
|
Accepted Date |
2016-05-10 |
Full Text |
Download |
Keyword |
3,3¢-bis(indolyl)methanes, salicylic acid, indole, 2-methylindole, green |
Volume |
Vol.45 No.1 (January 2018) |
DOI |
|
Citation |
Banari H., Kiyani H. and Pourali A., Green Synthesis of Bis(indolyl)methanes Catalysed by Salicylic Acid, Chiang Mai J. Sci., 2018; 45(1): 413-420. |
SDGs |
|
| View:606 Download:335 | |
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