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Three Component Coupling Catalyzed by Nickel (II) Chloride Hexahydrate: Synthesis of α-Amino Phosphonates


Paper Type 
Contributed Paper
Title 
Three Component Coupling Catalyzed by Nickel (II) Chloride Hexahydrate: Synthesis of α-Amino Phosphonates
Author 
Abbas Teimouri [a] Alireza Najafi Chermahini [b], Mehdi Narimani [a]
Email 
a_teimouri@pnu,ac.ir
Abstract:
 A simple highly versatile and efficient method has been developed for the three-component coupling of aromatic aldehydes, aromatic amines and diethyl phosphate in the presence of a catalytic amount of nickel (II) chloride hexahydrate in acetonitrile. The advantages of this method are high yield, mild reaction conditions and easy work up procedure.

Start & End Page 
228 - 237
Received Date 
2013-01-10
Revised Date 
Accepted Date 
2013-11-30
Full Text 
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Keyword 
Nickel (II) chloride hexahydrate, green synthesis, α-amino phosphonates
Volume 
Vol.42 No.1 (JANUARY 2015)
DOI 
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Chiang Mai Journal of Science

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