Three Component Coupling Catalyzed by Nickel (II) Chloride Hexahydrate: Synthesis of α-Amino Phosphonates

Abbas Teimouri [a] Alireza Najafi Chermahini [b], Mehdi Narimani [a]
* Author for corresponding; e-mail address: a_teimouri@pnu,ac.ir
Volume: Vol.42 No.1 (JANUARY 2015)
Research Article
DOI:
Received: 10 January 2013, Revised: -, Accepted: 30 November 2013, Published: -

Citation: Chermahini A.T..A.N. and Narimani M., Three Component Coupling Catalyzed by Nickel (II) Chloride Hexahydrate: Synthesis of α-Amino Phosphonates, Chiang Mai Journal of Science, 2015; 42(1): 228-237.

Abstract

A simple highly versatile and efficient method has been developed for the three-component coupling of aromatic aldehydes, aromatic amines and diethyl phosphate in the presence of a catalytic amount of nickel (II) chloride hexahydrate in acetonitrile. The advantages of this method are high yield, mild reaction conditions and easy work up procedure.

Keywords: Nickel (II) chloride hexahydrate, green synthesis, α-amino phosphonates

Chiang Mai Journal of Science

1,647

Q3 0.80

Q3 1.3

7 days

Outline

Figures and Tables