Inhibitory Activity of Blue Green Algae, Spirulina platensis Against Herpes Simplex Virus Type 1 and 2 Infection on Vero Cells
Yingmanee Tragoolpua* and Yuwadee Peerapornpisal* Author for corresponding; e-mail address: yboony@chiangmai.ac.th
Volume: Vol.32 No.2 (MAY 2005)
Short Communication
DOI:
Received: 8 July 2004, Revised: -, Accepted: 16 Febuary 2005, Published: -
Citation: Tragoolpua Y. and Peerapornpisal Y., Inhibitory Activity of Blue Green Algae, Spirulina platensis Against Herpes Simplex Virus Type 1 and 2 Infection on Vero Cells, Chiang Mai Journal of Science, 2005; 32(2): 149-153.
Abstract
Inhibitory activity of Spirulina platensis against herpes simplex virus type 1 and 2 was investigated in this study. Both types of herpes simplex viruses were treated with algal filtrate at non toxic concentrations and inhibition of virus infection was determined on Vero cells using plaque reduction assay. The results showed that the algal filtrate was exerted antiviral activities by interfering with viral adsorption. The inhibition of herpes simplex virus type 1 was 61% whereas herpes simplex virus type 2 was inhibited for 81.7% when treating with algal filtrate at concentration of 390.6 µg/ml. Moreover, exposure time of the algal filtrate and virus may also affect antiviral activity of the algal filtrate since shorter exposure time resulted in very low inhibition of virus infection.