Submit your paper 
Download Template JOURNAL DETAIL
Gelatin Microspheres Containing Multi-Walled Carbon Nanotubes: Preparation, Characterization, and Use as a Drug Carrier
Paper Type  |
Contributed Paper |
Title |
Gelatin Microspheres Containing Multi-Walled Carbon Nanotubes: Preparation, Characterization, and Use as a Drug Carrier |
Author |
Saowapa Thumsing [a,b] and Pitt Supaphol [a,b]* |
Email |
pitt.s@chula.ac.th |
|
Abstract: This work investigated how the incorporation of multi-walled carbon nanotubes (MWCNTs) into gelatin microspheres influences the effectiveness of microspheres as drug delivery systems by studying the adsorption of asiaticoside (AC) on the microspheres. We treated MWCNTs with a H2SO4/HNO3 solution. The treated MWCNTs were dispersed in deionized water and sonicated in an ultrasonic bath. The dispersion of treated MWCNTs was then mixed with the gelatin stock solution, and microsphere swelling and AC encapsulation efficiency were determined. Untreated gelatin microspheres were used for comparison. The experimental results indicated that the addition of the treated MWCNTs enhanced the mechanical stability of the gelatin microspheres. Furthermore, the addition of the treated MWCNTs to the gelatin microspheres increased AC encapsulation efficiency and slowed AC release. The maximum AC sorption capacities of the gelatin and the treated MWCNT-filled gelatin microspheres were 115.22 and 230.11 mg/g, respectively. In addition, cytotoxicity was investigated using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, which revealed that the treated MWCNT-filled gelatin microspheres did not affect murine fibroblast (L929) viability. Thus, the synthesized microspheres were biocompatible with the fibroblasts.
|
|
Start & End Page |
1287 - 1300 |
Received Date |
2013-08-14 |
Revised Date |
|
Accepted Date |
2014-03-24 |
Full Text |
Download |
Keyword |
Carbon nanotubes, Gelatin, Asiaticoside, Microsphere, Controlled release |
Volume |
Vol.41 No.5/2 (OCTOBER 2014) |
DOI |
|
Citation |
[a S.T., B] , [a P.S. and B]* , Gelatin Microspheres Containing Multi-Walled Carbon Nanotubes: Preparation, Characterization, and Use as a Drug Carrier, Chiang Mai Journal of Science, 2014; 41(5/2): 1287-1300. |
SDGs |
|
| View:634 Download:258 | |
RELATED ARTICLE
Optimization of Chitosan-Alginate Hydrogel Properties for Controlled Release of Urea
Article ID: e2025008
Author:Melody Kimi and Chee Jiun Chong
Vol.52 No.1 (January 2025) View: 246 Download:106
Article ID: e2025008
Author:Melody Kimi and Chee Jiun Chong
Vol.52 No.1 (January 2025) View: 246 Download:106
Effect of Pregelatinized Starch on the Properties of Poly (Vinyl Alcohol) Film for the Water-Soluble Laundry Bag
page: 1604 - 1617
Author:Montree Sangthongdee, Supanut Phattarateera and Poonsub Threepopnatkul
Vol.49 No.6 (November 2022) View: 727 Download:581
page: 1604 - 1617
Author:Montree Sangthongdee, Supanut Phattarateera and Poonsub Threepopnatkul
Vol.49 No.6 (November 2022) View: 727 Download:581
Performance of Shear Wave Speed Measurements by Using Reverberant Optical Coherence Elastography
page: 81 - 92
Author:Nirawit Kunanta, Fernando Zvietcovich, Kevin J. Parker, Jannick P. Rolland and Panomsak Meemon
Vol.49 No.1 (Special Issue I : Jan 2022) View: 1,252 Download:416
page: 81 - 92
Author:Nirawit Kunanta, Fernando Zvietcovich, Kevin J. Parker, Jannick P. Rolland and Panomsak Meemon
Vol.49 No.1 (Special Issue I : Jan 2022) View: 1,252 Download:416
Gold Nanoparticles Decorated on Carbon Nanotube Modified Screen-printed Electrode for Flow Injection Amperometric Determination of Methyldopa
page: 537 - 546
Author:Jantima Upan, Suwaphid Themsirimongkon, Surin Saipanya and Jaroon Jakmunee
Vol.46 No.3 (May 2019) View: 776 Download:214
page: 537 - 546
Author:Jantima Upan, Suwaphid Themsirimongkon, Surin Saipanya and Jaroon Jakmunee
Vol.46 No.3 (May 2019) View: 776 Download:214
Long-term Study of Cu/SiO2 Microspheres as Antimicrobial Additives in Paints
page: 523 - 536
Author:Kanita Boonruang, Panus Sundarapura and Wanwipa Siriwatwechakul*
Vol.46 No.3 (May 2019) View: 671 Download:239
page: 523 - 536
Author:Kanita Boonruang, Panus Sundarapura and Wanwipa Siriwatwechakul*
Vol.46 No.3 (May 2019) View: 671 Download:239
Micro-Solid Phase Extraction (m-SPE) Based on Alginate/Multi-walled Carbon Nanotubes Sorbent for the Determination of Bisphenol A in Canned Fruits
page: 2348 - 2360
Author:Ungku Amirul Arif Ungku Abdullah, Nor Suhaila Mohamad Hanapi, Wan Nazihah Wan Ibrahim, Nor’ashikin Saim and Noorfatimah Yahaya
Vol.45 No.6 (September 2018) View: 699 Download:314
page: 2348 - 2360
Author:Ungku Amirul Arif Ungku Abdullah, Nor Suhaila Mohamad Hanapi, Wan Nazihah Wan Ibrahim, Nor’ashikin Saim and Noorfatimah Yahaya
Vol.45 No.6 (September 2018) View: 699 Download:314
Preparation of Crosslinked Poly(lactic acid-co-glycidyl methacrylate) Microspheres by Phase Inversion Emulsification
page: 2048 - 2058
Author:Kamonchanok Thananukul, Atitsa Petchsuk, Wilairat Supmak, Preeyaporn Chaiyasat, Amorn Chaiyasat and Pakorn Opaprakasit
Vol.45 No.5 (Special 2018) View: 683 Download:275
page: 2048 - 2058
Author:Kamonchanok Thananukul, Atitsa Petchsuk, Wilairat Supmak, Preeyaporn Chaiyasat, Amorn Chaiyasat and Pakorn Opaprakasit
Vol.45 No.5 (Special 2018) View: 683 Download:275
Feasibility study of margarine substitute based on gelatin-oil emulsion gel
page: 505 - 514
Author:Wipawan Kangchai, Ratsamee Sangsirimongkolying and Pawadee Methacanon
Vol.45 No.1 (January 2018) View: 672 Download:330
page: 505 - 514
Author:Wipawan Kangchai, Ratsamee Sangsirimongkolying and Pawadee Methacanon
Vol.45 No.1 (January 2018) View: 672 Download:330
Scaffolds of Fish Skin Gelatin from Unicorn Leatherjackets (Aluterus monoceros) Reinforced with Chitosan for Bone Tissue Engineering
page: 1611 - 1623
Author:Safiah Saah, Kwunchit Oungbho* and Soottawat Benjakul
Vol.44 No.4 (October 2017) View: 785 Download:305
page: 1611 - 1623
Author:Safiah Saah, Kwunchit Oungbho* and Soottawat Benjakul
Vol.44 No.4 (October 2017) View: 785 Download:305
Kinetic Study of Ibuprofen Release from a pH- and Temperature-sensitive Hydrogel, Based on Poly(styrene-alt-maleic anhydride) Copolymer
page: 224 - 236
Author:Morteza Bahram, Fariba Hoseinpour, Naimeh Mohseni and Peyman Najafi-Moghaddam
Vol.44 No.1 (JANUARY 2017) View: 670 Download:468
page: 224 - 236
Author:Morteza Bahram, Fariba Hoseinpour, Naimeh Mohseni and Peyman Najafi-Moghaddam
Vol.44 No.1 (JANUARY 2017) View: 670 Download:468
Effect of Plasma Power on Copper Substrate Used for Synthesizing Carbon Nanotubes via
Alcohol Catalytic Chemical Vapor Deposition (ACVD) Technique
page: 339 - 344
Author:Sureewan Phunwaree*, Wim Nhuapeng, Dheerawan Boonyawan, and Wandee Thamjaree*
Vol.43 No.2 (SPECIAL ISSUE 1) View: 674 Download:197
page: 339 - 344
Author:Sureewan Phunwaree*, Wim Nhuapeng, Dheerawan Boonyawan, and Wandee Thamjaree*
Vol.43 No.2 (SPECIAL ISSUE 1) View: 674 Download:197
Optimization of the Preparation of Gelatin Hydrolysates with Antioxidative Activity from Lizardfish (Saurida spp.) Scales Gelatin
page: 68 - 79
Author:Sutee Wangtueai [a, b]*, Susanne Siebenhandl-Ehn [c] and Dietmar Haltrich [c]
Vol.43 No.1 (JANUARY 2016) View: 778 Download:438
page: 68 - 79
Author:Sutee Wangtueai [a, b]*, Susanne Siebenhandl-Ehn [c] and Dietmar Haltrich [c]
Vol.43 No.1 (JANUARY 2016) View: 778 Download:438
Candle Flame Synthesis and Electrochemical Behavior of Chain-like Carbon Nano-onions on 304 Stainless Steel
page: 745 - 751
Author:Saifon Kruehong, Chaiyaput Kruehong, Prinya Chindaprasirt and Apichart Artnaseaw
Vol.42 No.3 (JULY 2015) View: 681 Download:187
page: 745 - 751
Author:Saifon Kruehong, Chaiyaput Kruehong, Prinya Chindaprasirt and Apichart Artnaseaw
Vol.42 No.3 (JULY 2015) View: 681 Download:187
Slow Release Fertilizer from Core-Shell Electrospun Fibers
page: 775 - 782
Author:Piyaporn Kampeerapappun*[a] and Nipon Phanomkate[b]
Vol.40 No.4 (OCTOBER 2013) View: 651 Download:214
page: 775 - 782
Author:Piyaporn Kampeerapappun*[a] and Nipon Phanomkate[b]
Vol.40 No.4 (OCTOBER 2013) View: 651 Download:214
Preparation of Carbon Nanotubes by Catalytic
Decomposition of Alcohol at Low Pressure
page: 427 - 432
Author:Pisanunak Chiwsitthiprapai [a], Sutichai Chaisitsak*[a] and Pavan Siamchai [b]
Vol.32 No.3 (SEPTEMBER 2005) View: 637 Download:199
page: 427 - 432
Author:Pisanunak Chiwsitthiprapai [a], Sutichai Chaisitsak*[a] and Pavan Siamchai [b]
Vol.32 No.3 (SEPTEMBER 2005) View: 637 Download:199
The Uniformity of Carbon Nanotubes Synthesized by
Hot Carbon-filament Enhanced CVD
page: 411 - 416
Author:Sutichai Chaisitsak*[a], Akira Y Yamada amada [b] and Mak Makoto oto K Konagai onagai [b]
Vol.32 No.3 (SEPTEMBER 2005) View: 648 Download:182
page: 411 - 416
Author:Sutichai Chaisitsak*[a], Akira Y Yamada amada [b] and Mak Makoto oto K Konagai onagai [b]
Vol.32 No.3 (SEPTEMBER 2005) View: 648 Download:182
High Performance Liquid Chromatographic Analysis
of Asiaticoside in Centella asiatica (L.) Urban
page: 521 - 525
Author:Prateek K. Jain and Ram K. Agrawal
Vol.35 No.3 (SEPTEMBER 2008) View: 683 Download:392
page: 521 - 525
Author:Prateek K. Jain and Ram K. Agrawal
Vol.35 No.3 (SEPTEMBER 2008) View: 683 Download:392
Synthesis of Carbon Nanoparticles Using Thermal
Co-pyrolysis of Ferrocene and Naphthalene Mixture
page: 379 - 383
Author:Tawatchai Charinpanitkul [a]*, Noriaki Sano [b], P ramote Puengjinda [a] +, P oonlasak Muthak arn [
Vol.32 No.3 (SEPTEMBER 2005) View: 1,126 Download:177
page: 379 - 383
Author:Tawatchai Charinpanitkul [a]*, Noriaki Sano [b], P ramote Puengjinda [a] +, P oonlasak Muthak arn [
Vol.32 No.3 (SEPTEMBER 2005) View: 1,126 Download:177
Copyrights © Since 2021 All Rights Reserved by Chiang Mai Journal of Science