Chiang Mai Journal of Science, Faculty of Science, Chiang Mai University

1.3

2024CiteScore

49th percentile

Journal Volumes

Submit your paper

Download Template

JOURNAL DETAIL

Gelatin Microspheres Containing Multi-Walled Carbon Nanotubes: Preparation, Characterization, and Use as a Drug Carrier

Paper Type	Contributed Paper
Title	Gelatin Microspheres Containing Multi-Walled Carbon Nanotubes: Preparation, Characterization, and Use as a Drug Carrier
Author	Saowapa Thumsing [a,b] and Pitt Supaphol [a,b]*
Email	pitt.s@chula.ac.th
Abstract: This work investigated how the incorporation of multi-walled carbon nanotubes (MWCNTs) into gelatin microspheres influences the effectiveness of microspheres as drug delivery systems by studying the adsorption of asiaticoside (AC) on the microspheres. We treated MWCNTs with a H₂SO₄/HNO₃ solution. The treated MWCNTs were dispersed in deionized water and sonicated in an ultrasonic bath. The dispersion of treated MWCNTs was then mixed with the gelatin stock solution, and microsphere swelling and AC encapsulation efficiency were determined. Untreated gelatin microspheres were used for comparison. The experimental results indicated that the addition of the treated MWCNTs enhanced the mechanical stability of the gelatin microspheres. Furthermore, the addition of the treated MWCNTs to the gelatin microspheres increased AC encapsulation efficiency and slowed AC release. The maximum AC sorption capacities of the gelatin and the treated MWCNT-filled gelatin microspheres were 115.22 and 230.11 mg/g, respectively. In addition, cytotoxicity was investigated using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, which revealed that the treated MWCNT-filled gelatin microspheres did not affect murine fibroblast (L929) viability. Thus, the synthesized microspheres were biocompatible with the fibroblasts.
Start & End Page	1287 - 1300
Received Date	2013-08-14
Revised Date
Accepted Date	2014-03-24
Full Text	Download
Keyword	Carbon nanotubes, Gelatin, Asiaticoside, Microsphere, Controlled release
Volume	Vol.41 No.5/2 (OCTOBER 2014)
DOI
Citation	[a S.T., B] , [a P.S. and B]* , Gelatin Microspheres Containing Multi-Walled Carbon Nanotubes: Preparation, Characterization, and Use as a Drug Carrier, Chiang Mai Journal of Science, 2014; 41(5/2): 1287-1300.
View:798 Download:296

Optimization of Chitosan-Alginate Hydrogel Properties for Controlled Release of Urea
Article ID: e2025008
Author:Melody Kimi and Chee Jiun Chong
Vol.52 No.1 (January 2025) View: 685 Download:824

Effect of Pregelatinized Starch on the Properties of Poly (Vinyl Alcohol) Film for the Water-Soluble Laundry Bag
page: 1604 - 1617
Author:Montree Sangthongdee, Supanut Phattarateera and Poonsub Threepopnatkul
Vol.49 No.6 (November 2022) View: 977 Download:767

Performance of Shear Wave Speed Measurements by Using Reverberant Optical Coherence Elastography
page: 81 - 92
Author:Nirawit Kunanta, Fernando Zvietcovich, Kevin J. Parker, Jannick P. Rolland and Panomsak Meemon
Vol.49 No.1 (Special Issue I : Jan 2022) View: 1,512 Download:571

Gold Nanoparticles Decorated on Carbon Nanotube Modified Screen-printed Electrode for Flow Injection Amperometric Determination of Methyldopa
page: 537 - 546
Author:Jantima Upan, Suwaphid Themsirimongkon, Surin Saipanya and Jaroon Jakmunee
Vol.46 No.3 (May 2019) View: 1,000 Download:262

Long-term Study of Cu/SiO2 Microspheres as Antimicrobial Additives in Paints
page: 523 - 536
Author:Kanita Boonruang, Panus Sundarapura and Wanwipa Siriwatwechakul*
Vol.46 No.3 (May 2019) View: 890 Download:289

Micro-Solid Phase Extraction (m-SPE) Based on Alginate/Multi-walled Carbon Nanotubes Sorbent for the Determination of Bisphenol A in Canned Fruits
page: 2348 - 2360
Author:Ungku Amirul Arif Ungku Abdullah, Nor Suhaila Mohamad Hanapi, Wan Nazihah Wan Ibrahim, Nor’ashikin Saim and Noorfatimah Yahaya
Vol.45 No.6 (September 2018) View: 921 Download:351

Preparation of Crosslinked Poly(lactic acid-co-glycidyl methacrylate) Microspheres by Phase Inversion Emulsification
page: 2048 - 2058
Author:Kamonchanok Thananukul, Atitsa Petchsuk, Wilairat Supmak, Preeyaporn Chaiyasat, Amorn Chaiyasat and Pakorn Opaprakasit
Vol.45 No.5 (Special 2018) View: 893 Download:322

Feasibility study of margarine substitute based on gelatin-oil emulsion gel
page: 505 - 514
Author:Wipawan Kangchai, Ratsamee Sangsirimongkolying and Pawadee Methacanon
Vol.45 No.1 (January 2018) View: 879 Download:462

Scaffolds of Fish Skin Gelatin from Unicorn Leatherjackets (Aluterus monoceros) Reinforced with Chitosan for Bone Tissue Engineering
page: 1611 - 1623
Author:Safiah Saah, Kwunchit Oungbho* and Soottawat Benjakul
Vol.44 No.4 (October 2017) View: 960 Download:389

Kinetic Study of Ibuprofen Release from a pH- and Temperature-sensitive Hydrogel, Based on Poly(styrene-alt-maleic anhydride) Copolymer
page: 224 - 236
Author:Morteza Bahram, Fariba Hoseinpour, Naimeh Mohseni and Peyman Najafi-Moghaddam
Vol.44 No.1 (JANUARY 2017) View: 892 Download:676

Effect of Plasma Power on Copper Substrate Used for Synthesizing Carbon Nanotubes via Alcohol Catalytic Chemical Vapor Deposition (ACVD) Technique
page: 339 - 344
Author:Sureewan Phunwaree*, Wim Nhuapeng, Dheerawan Boonyawan, and Wandee Thamjaree*
Vol.43 No.2 (SPECIAL ISSUE 1) View: 871 Download:266

Optimization of the Preparation of Gelatin Hydrolysates with Antioxidative Activity from Lizardfish (Saurida spp.) Scales Gelatin
page: 68 - 79
Author:Sutee Wangtueai [a, b]*, Susanne Siebenhandl-Ehn [c] and Dietmar Haltrich [c]
Vol.43 No.1 (JANUARY 2016) View: 1,074 Download:533

Candle Flame Synthesis and Electrochemical Behavior of Chain-like Carbon Nano-onions on 304 Stainless Steel
page: 745 - 751
Author:Saifon Kruehong, Chaiyaput Kruehong, Prinya Chindaprasirt and Apichart Artnaseaw
Vol.42 No.3 (JULY 2015) View: 896 Download:219

Slow Release Fertilizer from Core-Shell Electrospun Fibers
page: 775 - 782
Author:Piyaporn Kampeerapappun*[a] and Nipon Phanomkate[b]
Vol.40 No.4 (OCTOBER 2013) View: 857 Download:268

Preparation of Carbon Nanotubes by Catalytic Decomposition of Alcohol at Low Pressure
page: 427 - 432
Author:Pisanunak Chiwsitthiprapai [a], Sutichai Chaisitsak*[a] and Pavan Siamchai [b]
Vol.32 No.3 (SEPTEMBER 2005) View: 807 Download:243

The Uniformity of Carbon Nanotubes Synthesized by Hot Carbon-filament Enhanced CVD
page: 411 - 416
Author:Sutichai Chaisitsak*[a], Akira Y Yamada amada [b] and Mak Makoto oto K Konagai onagai [b]
Vol.32 No.3 (SEPTEMBER 2005) View: 819 Download:239

High Performance Liquid Chromatographic Analysis of Asiaticoside in Centella asiatica (L.) Urban
page: 521 - 525
Author:Prateek K. Jain and Ram K. Agrawal
Vol.35 No.3 (SEPTEMBER 2008) View: 937 Download:621

Synthesis of Carbon Nanoparticles Using Thermal Co-pyrolysis of Ferrocene and Naphthalene Mixture
page: 379 - 383
Author:Tawatchai Charinpanitkul [a]*, Noriaki Sano [b], P ramote Puengjinda [a] +, P oonlasak Muthak arn [
Vol.32 No.3 (SEPTEMBER 2005) View: 1,296 Download:244

Search in this journal

Document Search

Author Search

A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z

Chiang Mai Journal of Science

Journal Volumes

JOURNAL DETAIL

Gelatin Microspheres Containing Multi-Walled Carbon Nanotubes: Preparation, Characterization, and Use as a Drug Carrier

RELATED ARTICLE

Search in this journal

Popular Search

Chiang Mai Journal of Science