Chiang Mai Journal of Science

In vitro Study on antifungal activity of Achillea wilhelmsii flower essential oil against twenty strains of Candida albicans

Paper Type	Contributed Paper
Title	In vitro Study on antifungal activity of Achillea wilhelmsii flower essential oil against twenty strains of Candida albicans
Author	Leila Amjad*[a], Kobra Mousavidehmourdi [b], Zahra Rezvani [c]
Email	Amjad.leila@gmail.com; Amjad@iaufala.ac.ir.
Abstract:  Infection diseases always were important worry. In the past decade numerous reports of treatment failures are reported. It is important to increase effective therapy. The aim of this study was in vitro studing of antifungal effects of the flowers essential oil of Achillea wilhelmsii C. Koch. In this study essential oil was obtained by hydro-distillation using Clevenger type apparatus for 3h. It was tested in vitro against 20 fungi strains. Several dilution of essential oil (10%, 15%, and 20%) was prepared. Antifungal activity was tested by using microdilution MIC determination, disk diffusion assay and agar well diffusion assay. Data were analyzed by ANOVA test in the P-Value< 0.05. The results illustrated that essential oil in dilution 20% has more inhibitor activity against 20 Strains of Candida albicans. The results of the present project indicate that the Achillea wilhelmsii flowers inhibited fungi growth but their effectiveness varied. Therefore we will be able perform researches with extraction of this plant effective compound for the treantment of infectious disease.
Start & End Page	1058 - 1064
Received Date	2013-04-22
Revised Date
Accepted Date	2013-05-30
Full Text	Download
Keyword	Achillea wilhelmsii, Candida albicans, Essential Oil
Volume	Vol.41 No.5/1 (OCTOBER 2014)
DOI
Citation	Amjad L., Mousavidehmourdi K. and Rezvani Z., In vitro Study on antifungal activity of Achillea wilhelmsii flower essential oil against twenty strains of Candida albicans , Chiang Mai J. Sci., 2014; 41(5/1): 1058-1064.
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