Chiang Mai Journal of Science

Print ISSN: 0125-2526 | eISSN : 2465-3845

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Ophiobolides, Polyketides Isolated from Ophiobolus sp. KTC 2293

Wilanfranco C. Tayone [a], Kazuaki Tanaka [b], and Noboru Takada*[b]
* Author for corresponding; e-mail address: takada@hirosaki-u.ac.jp
Volume: Vol.43 No.3 (APRIL 2016)
Research Article
DOI:
Received: 6 January 2015, Revised: -, Accepted: 27 April 2015, Published: -

Citation: Tayone W.C., Tanaka K. and Takada N., Ophiobolides, Polyketides Isolated from Ophiobolus sp. KTC 2293, Chiang Mai Journal of Science, 2016; 43(3): 477-483.

Abstract

 Three new polyketides, ophiobolides A, B, and C, were isolated from the culture broth of Ophiobolus sp. KTC 2293 along with structurally related achaetolide. The structures of these polyketides were elucidated on the basis of NMR and MS analyses. Ophiobolide B showed a weak antifungal activity against Cochliobolus miyabeanus.

Keywords: ophiobolide, polyketides, Ophiobolus, structural elucidation, antifungal activity

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