Chiang Mai Journal of Science

Ophiobolides, Polyketides Isolated from Ophiobolus sp. KTC 2293

Paper Type	Contributed Paper
Title	Ophiobolides, Polyketides Isolated from Ophiobolus sp. KTC 2293
Author	Wilanfranco C. Tayone [a], Kazuaki Tanaka [b], and Noboru Takada*[b]
Email	takada@hirosaki-u.ac.jp
Abstract:  Three new polyketides, ophiobolides A, B, and C, were isolated from the culture broth of Ophiobolus sp. KTC 2293 along with structurally related achaetolide. The structures of these polyketides were elucidated on the basis of NMR and MS analyses. Ophiobolide B showed a weak antifungal activity against Cochliobolus miyabeanus.
Start & End Page	477 - 483
Received Date	2015-01-06
Revised Date
Accepted Date	2015-04-27
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Keyword	ophiobolide, polyketides, Ophiobolus, structural elucidation, antifungal activity
Volume	Vol.43 No.3 (APRIL 2016)
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