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Stability of Vancomycin 31 mg/mL in Extemporaneous Eye Drops Determined with Capillary Electrophoresis
Paper Type  |
Contributed Paper |
Title |
Stability of Vancomycin 31 mg/mL in Extemporaneous Eye Drops Determined with Capillary Electrophoresis |
Author |
Anutra Khangtragool, Sineenart Santidherakul and Phuriwat Leesawat |
Email |
akhangtr@med.cmu.ac.th |
|
Abstract: This study evaluates the stability of extemporaneous ophthalmic antibiotic preparations made from a commercially available injection of vancomycin of 31 mg/mL and stored at 2-8°C and 28°C for 3 months. After various storage times, the stability was determined by capillary electrophoresis. Solutions of vancomycin 31 mg/mL in Tear Naturale ПTM were found to be stable after storage at 2-8°C and 28°C for 28 days, respectively. Vancomycin 31 mg/mL in extemporaneous eye drops prepared and supplied by a pharmacy should be stored at 2-8°C for less than 28 days. |
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Start & End Page |
533 - 540 |
Received Date |
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Revised Date |
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Accepted Date |
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Full Text |
Download |
Keyword |
extemporaneous eye drops, stability, vancomycin, capillary electrophoresis |
Volume |
Vol.38 No.4 (OCTOBER 2011) |
DOI |
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Citation |
Khangtragool A., Santidherakul S. and Leesawat P.., Stability of Vancomycin 31 mg/mL in Extemporaneous Eye Drops Determined with Capillary Electrophoresis, Chiang Mai Journal of Science, 2011; 38(4): 533-540. |
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