Gallocyanine as An Efficient Catalyst for Synthesis of Benzimidazoles in Aqueous Ethanol
Min Zhang, Chunshu Liao, Zhenyuan Lin, Bin Li, Yibiao Li and Lu Chen** Author for corresponding; e-mail address: wyuchemcl@126.com
Volume: Vol.46 No.4 (July 2019)
Research Article
DOI:
Received: 12 October 2018, Revised: -, Accepted: 16 December 2018, Published: -
Citation: Zhang M., Liao C., Lin Z., Li B., Li Y. and Chen L., Gallocyanine as An Efficient Catalyst for Synthesis of Benzimidazoles in Aqueous Ethanol, Chiang Mai Journal of Science, 2019; 46(4): 727-732.
Abstract
The benzimidazole derivatives have been obtained catalyzed by gallocyanine. A wide range of aromatic aldehydes easily undergo condensation with substituted o-phenylendiamine under mild conditions to afford the target molecules in excellent yields. The products were obtained in 80–93% yields in 30–80 min. The method has several advantages such as use of green solvent, easy work-up, excellent yield and avoiding use of inconvenient preparation of catalyst. Meanwhile, the catalyst gallocyanine is a kind of inexpensive catalyst, which might be applied to broad green catalytic system.