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Strong fluctuations in DNA Unzipping


Paper Type 
Contributed Paper
Title 
Strong fluctuations in DNA Unzipping
Author 
Sitichoke Amnuanpol*
Email 
sitichok@tu.ac.th
Abstract:
            In a living cell two strands of nucleotides forming a double helix are unbound, in response to enzymatic force, to the independent strands. Such force-induced structural transformation of DNA is studied in the context of phase transition. Fluctuations around a double helix, which is the ground-state energy configuration, are so strong that the mean field description is no longer valid. Treating two strands of nucleotides as the one dimensional continuous entities interacting via a potential, the growth of the helix wavevector under recursion relations, derived by the momentum shell renormalization group, accounts for the rapidly spatial variation of two unbound strands.        

Start & End Page 
980 - 989
Received Date 
2013-11-26
Revised Date 
Accepted Date 
2014-03-07
Full Text 
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Keyword 
DNA unzipping, force-extension curve, momentum shell renormalization group
Volume 
Vol.42 No.4 (OCTOBER 2015)
DOI 
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Chiang Mai Journal of Science

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