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Antitubercular and Antiplasmodial Prenylated Flavones from the Roots of Artocarpus altilis
Paper Type  |
Contributed Paper |
Title |
Antitubercular and Antiplasmodial Prenylated Flavones from the Roots of Artocarpus altilis |
Author |
Surat Boonphong , Apiwat Baramee, Prasat Kittakoop , and Pakawan Puangsombat |
Email |
pakawan@science.cmu.ac.th |
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Abstract: Antitubercular and antimalarial activity-guided study of the roots of Artocarpus altilis led to the isolation of nine prenylated flavones. Cycloartocarpin (1), artocarpin (2), and chaplashin (3) were isolated from the dichloromethane extract of the root stems, whereas morusin (4), cudraflavone B (5), cycloartobiloxanthone (6), artonin E (7), cudraflavone C (8) and artobiloxanthone (9) were found in the root barks. The isolated compounds exhibited antitubercular and antiplasmodial activities, and also showed moderate cytotoxicity against KB (human oral epidermoid carcinoma) and BC (human breast cancer) cell lines.
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Start & End Page |
339 - 344 |
Received Date |
2007-05-03 |
Revised Date |
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Accepted Date |
2007-05-23 |
Full Text |
Download |
Keyword |
Artocarpus altilis, prenylated flavones, antituberculosis, antimalarial activity |
Volume |
Vol.34 No.3 (SEPTEMBER 2007) |
DOI |
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SDGs |
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