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Synthesis and Characterisation of Poly(2-hydroxyethyl methacrylate-co-methyl acrylate) Hydrogels for Use as Temporary Skin Substitutes


Paper Type 
Opinion
Title 
Synthesis and Characterisation of Poly(2-hydroxyethyl methacrylate-co-methyl acrylate) Hydrogels for Use as Temporary Skin Substitutes
Author 
Tiwaporn Siriwittayakorn [a], Nantarat Suebsanit [a], Robert Molloy [a], Paisit Siriwittayakorn [b] and Malinee Prasitsilp [c]
Email 
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Abstract:
Homopolymers and copolymers of 2-hydroxyethyl methacrylate and methyl acrylate were synthesized in the form of thin sheets via in situ bulk polymerization in purpose-designed moulds. The methyl acrylate contents in the copolymers were in the range of 0-25% by weight. Linear relationships between the hydrogel properties of the copolymers and their methyl acrylate contents were clearly shown. As the amount of methyl acrylate in the copolymer increased, the equilibrium water content, equilibrium water retention, water vapour transmission, glass transition temperature and tensile stress at break all decreased. However, the thermal stability of the copolymers showed the opposite trend. Taking all of these properties into consideration, the copolymers studied here were viewed as having potential for use as temporary skin substitutes.
Start & End Page 
71 - 82
Received Date 
2001-05-28
Revised Date 
Accepted Date 
2001-09-11
Full Text 
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Keyword 
Poly(2-hydroxyethyl methacrylate), Poly(2-hydroxyethyl methacrylate-co-methyl acrylate), poly (methyl acrylate), synthetic hydrogels, temporary skin substitutes
Volume 
Vol.28 No.2 (DECEMBER 2001)
DOI 
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Chiang Mai Journal of Science

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