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A Poly(pyrrole-3-carboxylic acid) Thin Film Modified Screen Printed Carbon Electrode as Highly Sensitive and Selective Label-free Electrochemical Immunosensing Platform
Paper Type  |
Contributed Paper |
Title |
A Poly(pyrrole-3-carboxylic acid) Thin Film Modified Screen Printed Carbon Electrode as Highly Sensitive and Selective Label-free Electrochemical Immunosensing Platform |
Author |
Supakiet Chanarsa, Chammari Pothipor, Nawee Kungwan and Kontad Ounnunkad |
Email |
kontad.ounnunkad@cmu.ac.th, suriyacmu@yahoo.com |
|
Abstract: Giving good stability and sensitivity of the low-cost electrochemical immunosensor is achieved using a conducting poly(pyrrole-3-carboxylic acid) (PP3C) film on a screen-printed carbon electrode (SPCE). The PP3C film offers high density surface carboxylic groups, on which can be covalently conjugated with capturing antibodies, and improves electrode reactivity. Our simple immunosensor exhibitessatisfactory sensitivity, selectivity, stability, reproducibility, and regenerability for the detection of human immunoglobulin G (IgG). The proposed sensitive immunosensor provides a detection limit of 0.120 ng mL-1 and a sensitivity of 3.61 μA cm-2 mL ng-1, which thus is promising for clinical applications. |
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Start & End Page |
530 - 541 |
Received Date |
2019-07-23 |
Revised Date |
|
Accepted Date |
2019-10-23 |
Full Text |
Download |
Keyword |
poly(pyrrole-3-carboxylic acid), immunosensor, screen-printed carbon electrode, label-free detection, immunoglobulin G |
Volume |
Vol.47 No.3 (May 2020) |
DOI |
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Citation |
Chanarsa S., Pothipor C., Kungwan N. and Ounnunkad K., A Poly(pyrrole-3-carboxylic acid) Thin Film Modified Screen Printed Carbon Electrode as Highly Sensitive and Selective Label-free Electrochemical Immunosensing Platform, Chiang Mai Journal of Science, 2020; 47(3): 530-541. |
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