Chiang Mai Journal of Science

Tetra-n-Butyl Ammonium Iodide Catalyzed Ring Opening of Epoxides with Sodium Saccharin

Paper Type	Contributed Paper
Title	Tetra-n-Butyl Ammonium Iodide Catalyzed Ring Opening of Epoxides with Sodium Saccharin
Author	Sadia Faiz, Ameer Fawad Zahoor*, Nasir Rasool, Muhammad Ajmal and Muhammad Irfan
Email	fawad.zahoor@gcuf.edu.pk, fawad.zahoor@gmail.com
Abstract:  Ring opening of phenyl glycidyl ether with sodium saccharin has been investigated and the methodology has been developed successfully. The product has been obtained via ring opening of the epoxide by the attack of the sodium saccharin at the less substituted carbon (SN2-type mechanism). We have also proposed a potential route to access 1,2-benzothiazine/ isoquinolines derivatives over a few steps.
Start & End Page	1229 - 1233
Received Date	2019-05-11
Revised Date
Accepted Date	2019-07-19
Full Text	Download
Keyword	sodium saccharin, phenyl glycidyl ether, nucleophilic ring opening, benzothiazine/ isoquinolines
Volume	Vol.46 No.6 (November 2019)
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