Chiang Mai Journal of Science

Essential Oil of Solanum spirale Fruits and Its Biological Activities

Paper Type	Contributed Paper
Title	Essential Oil of Solanum spirale Fruits and Its Biological Activities
Author	Sukanya Keawsa-ard [a], Boonsom Liawruangrath* [b], Saisunee Liawruangrath [c], Aphiwat Teerawutgulrag [c] Stephen G. Pyne [d]
Email	liawruangrath@gmail.com
Abstract:  The essential oil of Solanum spirale Roxb. unripe fruits was analyzed for the first time using GC-MS. Twenty-nine constituents were identified, constituting 82.11% of the total chromatographical oil components. The major components were n-hexadecanoic acid (56.01%), linolelic acid (9.71%), octadecanoic acid (4.41%), methyl plamitate (1.69%), tetradecanoic acid (1.55%), (E)-phytol (1.18%), n-hexanal (0.91%), methyl salicylate (0.83%), 4-hydroxy-4-methylpentan-2-one (0.81%), pentadecanoic acid (0.71%) and b-selinene (0.56%). The oil exhibited anticancer activities against MCF-7 (breast cancer) and NCI-H187 (small cell lung cancer) with the IC50 values of 23.17 and 49.07 µg/mL, respectively. It exhibited antituberculosis activity against Mycobacterium tuberculosis H37Ra with the MIC value of 50.0 µg/mL and it also showed moderately antibacterial activity against Escherichia coli and Staphylococcus aureus with the MIC values of 118 mg/mL.
Start & End Page	547 - 555
Received Date	2014-08-06
Revised Date
Accepted Date	2014-10-28
Full Text	Download
Keyword	Solanum spirale, unripe fruits, essential oil, anticancer activity, cytotoxic activity, antituberculosis activity, antibacterial activity
Volume	Vol.43 No.3 (APRIL 2016)
DOI
SDGs
View:595 Download:203